Literature DB >> 11160021

Expression, extracellular secretion, and immunogenicity of the Plasmodium falciparum sporozoite surface protein 2 in Salmonella vaccine strains.

O G Gómez-Duarte1, M F Pasetti, A Santiago, M B Sztein, S L Hoffman, M M Levine.   

Abstract

Deleting transmembrane alpha-helix motifs from Plasmodium falciparum sporozoite surface protein (SSP-2) allowed its secretion from Salmonella enterica serovar Typhimurium SL3261 and S. enterica serovar Typhi CVD 908-htrA by the Hly type I secretion system. In mice immunized intranasally, serovar Typhimurium constructs secreting SSP-2 stimulated greater gamma interferon splenocyte responses than did nonsecreting constructs (P = 0.04).

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Year:  2001        PMID： 11160021      PMCID： PMC98005          DOI： 10.1128/IAI.69.2.1192-1198.2001

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  42 in total

1.  Characterization of the gene encoding sporozoite surface protein 2, a protective Plasmodium yoelii sporozoite antigen.

Authors:  W O Rogers; M D Rogers; R C Hedstrom; S L Hoffman
Journal:  Mol Biochem Parasitol       Date:  1992-07       Impact factor: 1.759

2.  Evaluation of Salmonella typhimurium strains harbouring defined mutations in htrA and aroA in the murine salmonellosis model.

Authors:  S N Chatfield; K Strahan; D Pickard; I G Charles; C E Hormaeche; G Dougan
Journal:  Microb Pathog       Date:  1992-02       Impact factor: 3.738

3.  Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines.

Authors:  S K Hoiseth; B A Stocker
Journal:  Nature       Date:  1981-05-21       Impact factor: 49.962

4.  Novel use of anaerobically induced promoter, dmsA, for controlled expression of fragment C of tetanus toxin in live attenuated Salmonella enterica serovar Typhi strain CVD 908-htrA.

Authors:  N Orr; J E Galen; M M Levine
Journal:  Vaccine       Date:  2001-02-08       Impact factor: 3.641

5.  Characterization of Plasmodium falciparum sporozoite surface protein 2.

Authors:  W O Rogers; A Malik; S Mellouk; K Nakamura; M D Rogers; A Szarfman; D M Gordon; A K Nussler; M Aikawa; S L Hoffman
Journal:  Proc Natl Acad Sci U S A       Date:  1992-10-01       Impact factor: 11.205

6.  Protection against malaria by vaccination with sporozoite surface protein 2 plus CS protein.

Authors:  S Khusmith; Y Charoenvit; S Kumar; M Sedegah; R L Beaudoin; S L Hoffman
Journal:  Science       Date:  1991-05-03       Impact factor: 47.728

7.  Induction of murine cytotoxic T lymphocytes against Plasmodium falciparum sporozoite surface protein 2.

Authors:  B Wizel; W O Rogers; R A Houghten; D E Lanar; J A Tine; S L Hoffman
Journal:  Eur J Immunol       Date:  1994-07       Impact factor: 5.532

8.  Salmonella typhi vaccine strain CVD 908 expressing the circumsporozoite protein of Plasmodium falciparum: strain construction and safety and immunogenicity in humans.

Authors:  C Gonzalez; D Hone; F R Noriega; C O Tacket; J R Davis; G Losonsky; J P Nataro; S Hoffman; A Malik; E Nardin; M B Sztein; D G Heppner; T R Fouts; A Isibasi; M M Levine
Journal:  J Infect Dis       Date:  1994-04       Impact factor: 5.226

9.  Complete protection against Plasmodium yoelii by adoptive transfer of a CD8+ cytotoxic T-cell clone recognizing sporozoite surface protein 2.

Authors:  S Khusmith; M Sedegah; S L Hoffman
Journal:  Infect Immun       Date:  1994-07       Impact factor: 3.441

10.  Induction of nitric oxide synthase protects against malaria in mice exposed to irradiated Plasmodium berghei infected mosquitoes: involvement of interferon gamma and CD8+ T cells.

Authors:  M C Seguin; F W Klotz; I Schneider; J P Weir; M Goodbary; M Slayter; J J Raney; J U Aniagolu; S J Green
Journal:  J Exp Med       Date:  1994-07-01       Impact factor: 14.307
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  3 in total

1.  Immunization of volunteers with Salmonella enterica serovar Typhi strain Ty21a elicits the oligoclonal expansion of CD8+ T cells with predominant Vbeta repertoires.

Authors:  Rosângela Salerno-Gonçalves; Rezwanul Wahid; Marcelo B Sztein
Journal:  Infect Immun       Date:  2005-06       Impact factor: 3.441

2.  Enhanced immunity to Plasmodium falciparum circumsporozoite protein (PfCSP) by using Salmonella enterica serovar Typhi expressing PfCSP and a PfCSP-encoding DNA vaccine in a heterologous prime-boost strategy.

Authors:  Magaly Chinchilla; Marcela F Pasetti; Sandra Medina-Moreno; Jin Yuan Wang; Oscar G Gomez-Duarte; Rick Stout; Myron M Levine; James E Galen
Journal:  Infect Immun       Date:  2007-05-14       Impact factor: 3.441

Review 3.  Prospects for Malaria Vaccines: Pre-Erythrocytic Stages, Blood Stages, and Transmission-Blocking Stages.

Authors:  Jingtong Zheng; He Pan; Yinuo Gu; Xu Zuo; Nan Ran; Yuze Yuan; Chao Zhang; Fang Wang
Journal:  Biomed Res Int       Date:  2019-10-03       Impact factor: 3.411
  3 in total

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