PURPOSE: To compare viscocanalostomy, a nonpenetrating procedure for glaucoma treatment, with trabeculectomy. DESIGN: Randomized controlled trial. PARTICIPANTS: Twenty white subjects (20 eyes) with open-angle glaucoma with no history of surgery were enrolled. METHODS: Ten subjects were randomly assigned to viscocanalostomy according to Stegmann's technique and 10 subjects to a modified Cairns trabeculectomy. A complete ophthalmologic examination was performed the day before surgery and postoperatively. Further visits were scheduled monthly for 6 to 8 months after surgery. MAIN OUTCOME MEASURES: Success was defined as intraocular pressure (IOP) between 7 and 20 mmHg, with no medication. RESULTS: After a mean follow-up of 6 months (range, 6-8 months), success was obtained in 5 of 10 cases in the trabeculectomy group and in no case in the viscocanalostomy group. With Kaplan-Meier's method, subjects with viscocanalostomy showed shorter postoperative IOP-reduction periods than subjects undergoing trabeculectomy. CONCLUSIONS: According to the results of this short-term study, trabeculectomy was more effective than viscocanalostomy in lowering IOP in glaucomatous eyes of white patients.
RCT Entities:
PURPOSE: To compare viscocanalostomy, a nonpenetrating procedure for glaucoma treatment, with trabeculectomy. DESIGN: Randomized controlled trial. PARTICIPANTS: Twenty white subjects (20 eyes) with open-angle glaucoma with no history of surgery were enrolled. METHODS: Ten subjects were randomly assigned to viscocanalostomy according to Stegmann's technique and 10 subjects to a modified Cairns trabeculectomy. A complete ophthalmologic examination was performed the day before surgery and postoperatively. Further visits were scheduled monthly for 6 to 8 months after surgery. MAIN OUTCOME MEASURES: Success was defined as intraocular pressure (IOP) between 7 and 20 mmHg, with no medication. RESULTS: After a mean follow-up of 6 months (range, 6-8 months), success was obtained in 5 of 10 cases in the trabeculectomy group and in no case in the viscocanalostomy group. With Kaplan-Meier's method, subjects with viscocanalostomy showed shorter postoperative IOP-reduction periods than subjects undergoing trabeculectomy. CONCLUSIONS: According to the results of this short-term study, trabeculectomy was more effective than viscocanalostomy in lowering IOP in glaucomatous eyes of whitepatients.
Authors: S Roters; C Lüke; C P Jonescu-Cuypers; B F Engels; P C Jacobi; W Konen; G K Krieglstein Journal: Br J Ophthalmol Date: 2002-09 Impact factor: 4.638