Literature DB >> 11158148

Sterilization of Mycobacterium tuberculosis Erdman samples by antimicrobial fixation in a biosafety level 3 laboratory.

J R Schwebach1, W R Jacobs, A Casadevall.   

Abstract

Incomplete sterilization of Mycobacterium tuberculosis Erdman cultures followed 1 h of incubation in low concentrations of glutaraldehyde (0.5 and 1.0%) or azide. In contrast, 2.5% glutaraldehyde, paraformaldehyde (2 or 4%), Vesphine IIse or 5% formalin sterilized these samples after 1 h. These results suggest caution in removing fixed M. tuberculosis samples from biosafety level 3.

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Year:  2001        PMID: 11158148      PMCID: PMC87817          DOI: 10.1128/JCM.39.2.769-771.2001

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN: 0095-1137            Impact factor:   5.948


  7 in total

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Authors:  F M Collins; V Montalbine
Journal:  J Clin Microbiol       Date:  1976-11       Impact factor: 5.948

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Authors:  P A Griffiths; J R Babb; A P Fraise
Journal:  J Hosp Infect       Date:  1999-02       Impact factor: 3.926

7.  Molecular composition of the outermost capsular material of the tubercle bacillus.

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Journal:  Microbiology       Date:  1995-07       Impact factor: 2.777

  7 in total
  11 in total

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7.  Unexpected high prevalence of resistance-associated Rv0678 variants in MDR-TB patients without documented prior use of clofazimine or bedaquiline.

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8.  Phenylalanine-rich peptides potently bind ESAT6, a virulence determinant of Mycobacterium tuberculosis, and concurrently affect the pathogen's growth.

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10.  Expression of the ARPC4 subunit of human Arp2/3 severely affects mycobacterium tuberculosis growth and suppresses immunogenic response in murine macrophages.

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