Literature DB >> 11156232

PGP9.5 as a prognostic factor in pancreatic cancer.

E Tezel1, K Hibi, T Nagasaka, A Nakao.   

Abstract

The expression of PGP9.5 was evaluated using immunohistochemistry in 69 resected ductal carcinomas of the pancreas and in normal pancreatic tissue. Overexpression did not seem to differ with histological type or pathological stage. A significant negative correlation was found between overexpression of PGP9.5 and postoperative survival. Multivariate analysis also suggested PGP9.5 along with tumor stage and extrapancreatic plexus invasion as strong predictors of the outcome. This study suggests that PGP9.5 expression may be used as a marker for predicting the outcome of resection-treated pancreatic cancer patients.

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Year:  2000        PMID: 11156232

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN: 1078-0432            Impact factor:   12.531


  45 in total

1.  Prognostic relevance of ubiquitin C-terminal hydrolase L1 (UCH-L1) mRNA and protein expression in breast cancer patients.

Authors:  Christine Schröder; Karin Milde-Langosch; Florian Gebauer; Katharina Schmid; Volkmar Mueller; Ralph M Wirtz; Catherine Meyer-Schwesinger; Hartmut Schlüter; Guido Sauter; Udo Schumacher
Journal:  J Cancer Res Clin Oncol       Date:  2013-08-31       Impact factor: 4.553

2.  CpG methylation of ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) and P53 mutation pattern in sporadic colorectal cancer.

Authors:  Rania Abdelmaksoud-Dammak; Amena Saadallah-Kallel; Imen Miladi-Abdennadher; Lobna Ayedi; Abdelmajid Khabir; Tahia Sallemi-Boudawara; Mounir Frikha; Jamel Daoud; Raja Mokdad-Gargouri
Journal:  Tumour Biol       Date:  2015-08-28

3.  UCH-L1 promotes invasion of breast cancer cells through activating Akt signaling pathway.

Authors:  Yanhong Luo; Jianfeng He; Chunlin Yang; Matthew Orange; Xingcong Ren; Nick Blair; Tao Tan; Jin-Ming Yang; Hua Zhu
Journal:  J Cell Biochem       Date:  2017-07-31       Impact factor: 4.429

4.  Analysis of the human pancreatic stellate cell secreted proteome.

Authors:  Angela Y Wehr; Emma E Furth; Vineet Sangar; Ian A Blair; Kenneth H Yu
Journal:  Pancreas       Date:  2011-05       Impact factor: 3.327

5.  The exclusive effects of chaperonin on the behavior of proteins with 52 knot.

Authors:  Yani Zhao; Pawel Dabrowski-Tumanski; Szymon Niewieczerzal; Joanna I Sulkowska
Journal:  PLoS Comput Biol       Date:  2018-03-16       Impact factor: 4.475

6.  Multifarious proteomic signatures and regional heterogeneity in glioblastomas.

Authors:  Chul-Kee Park; Ji Hye Jung; Sung-Hye Park; Hee-Won Jung; Byung-Kyu Cho
Journal:  J Neurooncol       Date:  2009-02-15       Impact factor: 4.130

7.  MicroRNA, hsa-miR-200c, is an independent prognostic factor in pancreatic cancer and its upregulation inhibits pancreatic cancer invasion but increases cell proliferation.

Authors:  Jun Yu; Kenoki Ohuchida; Kazuhiro Mizumoto; Norihiro Sato; Tadashi Kayashima; Hayato Fujita; Kouhei Nakata; Masao Tanaka
Journal:  Mol Cancer       Date:  2010-06-28       Impact factor: 27.401

8.  Frequent CpG methylation of ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) in sporadic and hereditary Tunisian breast cancer patients: clinical significance.

Authors:  Fatma Trifa; Sondes Karray-Chouayekh; Zeineb Ben Jmaa; Emna Jmal; Abdelmajid Khabir; Tahia Sellami-Boudawara; Mounir Frikha; Jamel Daoud; Raja Mokdad-Gargouri
Journal:  Med Oncol       Date:  2013-01-13       Impact factor: 3.064

9.  Expression and functional studies of ubiquitin C-terminal hydrolase L1 regulated genes.

Authors:  Anjali Bheda; Julia Shackelford; Joseph S Pagano
Journal:  PLoS One       Date:  2009-08-26       Impact factor: 3.240

10.  Epigenetic control of the ubiquitin carboxyl terminal hydrolase 1 in renal cell carcinoma.

Authors:  Barbara Seliger; Diana Handke; Elisabeth Schabel; Juergen Bukur; Rudolf Lichtenfels; Reinhard Dammann
Journal:  J Transl Med       Date:  2009-10-26       Impact factor: 5.531

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