Literature DB >> 11153366

[Blaschko-linear dermatitis in adulthood (Grosshans-Marot disease) with antinuclear antibodies].

D Lipsker1, J Stark, G A Schneider.   

Abstract

E. Grosshans and L. Marot first described blaschkitis in 1990 as a linear inflammatory dermatitis following lines of Blaschko in an adult patient. We report another case which occurred in a 38-year-old woman who developed an extensive, linear, erythematosquamous dermatitis involving the face, all limbs and the trunk. The patient's serum tested positive for antinuclear antibodies at a dilution of 1:640. The lesions regressed spontaneously within 4 weeks. Blaschkitis is a distinct entity which corresponds neither to a known inflammatory dermatitis in the lines of Blaschko nor to an hamartoma nor to an X-linked disease. Cutaneous antigenic mosaicism, the expression of which might be induced by a viral infection, could trigger this localized inflammatory T-cell response. This hypothesis relates blaschkitis to other cutaneous autoimmune diseases, as does the presence of antinuclear antibodies. We therefore suggest renaming this type of inflammatory dermatitis Grosshans-Marot disease in honour to the dermatologists who first described the entity.

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Year:  2000        PMID: 11153366     DOI: 10.1007/s001050051214

Source DB:  PubMed          Journal:  Hautarzt        ISSN: 0017-8470            Impact factor:   0.751


  1 in total

1.  A Case of Blaschkitis with Features of Both Lichenoid and Spongiotic Dermatitis.

Authors:  Arghavan Azizpour; Maryam Nasimi; Zahra Safaie-Naraghi; Ifa Etesami
Journal:  Indian J Dermatol       Date:  2016 May-Jun       Impact factor: 1.494

  1 in total

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