Literature DB >> 11151694

Unusual pattern of leukoencephalopathy after morphine sulphate intoxication.

R Nanan1, H B von Stockhausen, B Petersen, L Solymosi, M Warmuth-Metz.   

Abstract

We report a 14-year-old girl with an unusual pattern of leukoencephalopathy after intentional intoxication with morphine sulphate tablets. Toxicological analysis showed exceedingly high levels of morphine and its metabolites. MRI disclosed a leukoencephalopathy with high signal from the centrum semiovale, corpus callosum and cerebellar white matter on T2-weighted images. These findings could be only partially explained by a hypoxic-ischaemic event; neurotoxic effects must be considered in this atypical leukoencephalopathy.

Entities:  

Mesh：

Substances：

Year:  2000        PMID： 11151694     DOI： 10.1007/s002340000442

Source DB:  PubMed          Journal:  Neuroradiology        ISSN： 0028-3940            Impact factor:   2.804


  10 in total

1.  Severe cerebellitis following methadone poisoning.

Authors:  Fionnghuala Mills; Suzanna C MacLennan; Catherine J Devile; Dawn E Saunders
Journal:  Pediatr Radiol       Date:  2007-10-20

2.  Malignant cerebellar edema in three-year-old girl following accidental opioid ingestion and fentanyl administration.

Authors:  Cathy H Chen; Alexander J Mullen; Dustin Hofstede; Tanvir Rizvi
Journal:  Neuroradiol J       Date:  2019-07-22

3.  The opioid system and brain development: effects of methadone on the oligodendrocyte lineage and the early stages of myelination.

Authors:  Allison A Vestal-Laborde; Andrew C Eschenroeder; John W Bigbee; Susan E Robinson; Carmen Sato-Bigbee
Journal:  Dev Neurosci       Date:  2014-08-19       Impact factor: 2.984

4.  Neuroimaging Findings in CHANTER Syndrome: A Case Series.

Authors:  K S Mallikarjun; M S Parsons; Z Nigogosyan; M S Goyal; R W Eldaya
Journal:  AJNR Am J Neuroradiol       Date:  2022-07-07       Impact factor: 4.966

5.  The molecular neurobiology and neuropathology of opioid use disorder.

Authors:  Christopher A Blackwood; Jean Lud Cadet
Journal:  Curr Res Neurobiol       Date:  2021-10-14

6.  Methadone-induced toxic leukoencephalopathy: MR imaging and MR proton spectroscopy findings.

Authors:  R A Salgado; P G Jorens; I Baar; P Cras; G Hans; P M Parizel
Journal:  AJNR Am J Neuroradiol       Date:  2009-11-05       Impact factor: 3.825

Review 7.  Endogenous and exogenous opioid effects on oligodendrocyte biology and developmental brain myelination.

Authors:  Brandon Velasco; Esraa Mohamed; Carmen Sato-Bigbee
Journal:  Neurotoxicol Teratol       Date:  2021-06-12       Impact factor: 4.071

Review 8.  Systematic Review of Pharmacological Properties of the Oligodendrocyte Lineage.

Authors:  Carla Marinelli; Thomas Bertalot; Morena Zusso; Stephen D Skaper; Pietro Giusti
Journal:  Front Cell Neurosci       Date:  2016-02-12       Impact factor: 5.505

9.  Outcomes associated with hospital admissions for accidental opioid overdose in British Columbia: a retrospective cohort study.

Authors:  Richard L Morrow; Ken Bassett; Malcolm Maclure; Colin R Dormuth
Journal:  BMJ Open       Date:  2019-05-05       Impact factor: 2.692

Review 10.  Opioid-induced toxic leukoencephalopathy: A case report and review of the literature.

Authors:  Taylor Wheaton; Brandon J Toll; Kara Breznak; Shonola Da-Silva; Joseph Melvin; Amit Misra; Steven W Hwang
Journal:  Heliyon       Date:  2019-12-11
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.