Literature DB >> 11150589

Relationship between sulfate groups and biological activities of fucans.

F Haroun-Bouhedja1, M Ellouali, C Sinquin, C Boisson-Vidal.   

Abstract

The anticoagulant and antiproliferative effects of low molecular weight fucans with different sulfate content were examined. The anticoagulant activity was determined by activated partial thromboplastin time and the antiproliferative one was achieved in vitro on CCL39 fibroblast cell line. The results showed that inhibitory effects of fucans on both coagulation and cell proliferation are dependent on their sulfation degree. Decreased sulfation diminishes the two activities not in the same manner: some low molecular weight fucan fractions with no anticoagulant activity retain their ability to inhibit cell growth.

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Year:  2000        PMID： 11150589     DOI： 10.1016/s0049-3848(00)00338-8

Source DB:  PubMed          Journal:  Thromb Res        ISSN： 0049-3848            Impact factor:   3.944


  33 in total

1.  Inhibitory effects of Fucoidan in 3T3-L1 adipocyte differentiation.

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Journal:  Mar Biotechnol (NY)       Date:  2008-12-10       Impact factor: 3.619

2.  Fucoidan in a 3D scaffold interacts with vascular endothelial growth factor and promotes neovascularization in mice.

Authors:  Agung Purnama; Rachida Aid-Launais; Oualid Haddad; Muriel Maire; Diego Mantovani; Didier Letourneur; Hanna Hlawaty; Catherine Le Visage
Journal:  Drug Deliv Transl Res       Date:  2015-04       Impact factor: 4.617

3.  Protective Effect of the Sulfated Agaran Isolated from the Red Seaweed Laurencia aldingensis Against Toxic Effects of the Venom of the Snake, Lachesis muta.

Authors:  Ana Cláudia Rodrigues da Silva; Luciana Garcia Ferreira; Maria Eugênia Rabello Duarte; Mutue Toyota Fujii; Eladio Flores Sanchez; Miguel Daniel Noseda; André Lopes Fuly
Journal:  Mar Biotechnol (NY)       Date:  2016-11-25       Impact factor: 3.619

4.  Immunomodulatory Properties of Highly Viscous Polysaccharide Extract from the Gagome Alga (Kjellmaniella crassifolia).

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Journal:  Plant Foods Hum Nutr       Date:  2012-01-31       Impact factor: 3.921

5.  Preliminary studies on the chemical characterization and antioxidant properties of acidic polysaccharides from Sargassum fusiforme.

Authors:  Jing Zhou; Nan Hu; Ya-lin Wu; Yuan-jiang Pan; Cui-rong Sun
Journal:  J Zhejiang Univ Sci B       Date:  2008-09       Impact factor: 3.066

6.  Chemical composition and antioxidant activities of Jeddah corniche algae, Saudi Arabia.

Authors:  Omar A Al-Amoudi; Hawazin H Mutawie; Asmita V Patel; Gerald Blunden
Journal:  Saudi J Biol Sci       Date:  2009-07       Impact factor: 4.219

Review 7.  Important determinants for fucoidan bioactivity: a critical review of structure-function relations and extraction methods for fucose-containing sulfated polysaccharides from brown seaweeds.

Authors:  Marcel Tutor Ale; Jørn D Mikkelsen; Anne S Meyer
Journal:  Mar Drugs       Date:  2011-10-24       Impact factor: 6.085

8.  Fucoidan partly prevents CCl4-induced liver fibrosis.

Authors:  Shinji Hayashi; Ayano Itoh; Katsuhiro Isoda; Masuo Kondoh; Masaya Kawase; Kiyohito Yagi
Journal:  Eur J Pharmacol       Date:  2007-11-17       Impact factor: 4.432

Review 9.  Antiviral Potential of Algae Polysaccharides Isolated from Marine Sources: A Review.

Authors:  Azin Ahmadi; Soheil Zorofchian Moghadamtousi; Sazaly Abubakar; Keivan Zandi
Journal:  Biomed Res Int       Date:  2015-09-21       Impact factor: 3.411

10.  Comparison of physicochemical characteristics and anticoagulant activities of polysaccharides from three sea cucumbers.

Authors:  Lan Luo; Mingyi Wu; Li Xu; Wu Lian; Jingying Xiang; Feng Lu; Na Gao; Chuang Xiao; Shengmin Wang; Jinhua Zhao
Journal:  Mar Drugs       Date:  2013-02-05       Impact factor: 5.118
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