Literature DB >> 11150505

A new diagnostic tool for neurocysticercosis is a member of a cestode specific hydrophobic ligand binding protein family.

N Saghir1, P J Conde, P M Brophy, J Barrett.   

Abstract

A protein of unknown function has been identified as a key serological tool for diagnosis of human tapeworm neurocysticercosis, a major worldwide neurological disease. Our own sequence analysis predicts that this protein is a member of a newly identified cestode specific oligomeric hydrophobic ligand binding protein family. In this report, using a rat cestode model, we confirm that homologues of this protein can bind fatty acids and their derivatives, and thus suggest a biological function for this key diagnostic tool.

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Year:  2000        PMID: 11150505     DOI: 10.1016/s0014-5793(00)02191-8

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  7 in total

1.  The Echinococcus granulosus antigen B gene family comprises at least 10 unique genes in five subclasses which are differentially expressed.

Authors:  Wenbao Zhang; Jun Li; Malcolm K Jones; Zhuangzhi Zhang; Li Zhao; David Blair; Donald Peter McManus
Journal:  PLoS Negl Trop Dis       Date:  2010-08-10

2.  Molecular cloning, expression, and serological evaluation of an 8-kilodalton subunit of antigen B from Echinococcus multilocularis.

Authors:  Wulamu Mamuti; Hiroshi Yamasaki; Yasuhito Sako; Minoru Nakao; Ning Xiao; Kazuhiro Nakaya; Naoki Sato; Dominique A Vuitton; Renaud Piarroux; Marshall W Lightowlers; Philip S Craig; Akira Ito
Journal:  J Clin Microbiol       Date:  2004-03       Impact factor: 5.948

3.  Characterization of the 8-kilodalton antigens of Taenia solium metacestodes and evaluation of their use in an enzyme-linked immunosorbent assay for serodiagnosis.

Authors:  Kathy Hancock; Azra Khan; Fatima B Williams; Melinda L Yushak; Sowmya Pattabhi; John Noh; Victor C W Tsang
Journal:  J Clin Microbiol       Date:  2003-06       Impact factor: 5.948

4.  Characterisation of the native lipid moiety of Echinococcus granulosus antigen B.

Authors:  Gonzalo Obal; Ana Lía Ramos; Valeria Silva; Analía Lima; Carlos Batthyany; María Inés Bessio; Fernando Ferreira; Gustavo Salinas; Ana María Ferreira
Journal:  PLoS Negl Trop Dis       Date:  2012-05-15

5.  Characterisation of Antigen B Protein Species Present in the Hydatid Cyst Fluid of Echinococcus canadensis G7 Genotype.

Authors:  Ana Maite Folle; Eduardo S Kitano; Analía Lima; Magdalena Gil; Marcela Cucher; Gustavo Mourglia-Ettlin; Leo K Iwai; Mara Rosenzvit; Carlos Batthyány; Ana María Ferreira
Journal:  PLoS Negl Trop Dis       Date:  2017-01-03

6.  Structural and binding properties of two paralogous fatty acid binding proteins of Taenia solium metacestode.

Authors:  Seon-Hee Kim; Young-An Bae; Hyun-Jong Yang; Joo-Ho Shin; Sylvia Paz Diaz-Camacho; Yukifumi Nawa; Insug Kang; Yoon Kong
Journal:  PLoS Negl Trop Dis       Date:  2012-10-25

7.  Lipid binding proteins from parasitic platyhelminthes.

Authors:  Gabriela Alvite; Adriana Esteves
Journal:  Front Physiol       Date:  2012-09-12       Impact factor: 4.566

  7 in total

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