Literature DB >> 11148420

[Benign solitary tumors of the peripheral nerves].

G Chick1, J Y Alnot, O Silbermann-Hoffman.   

Abstract

Solitary tumors of the peripheral nerves are uncommon and found to be benign in 90 p. 100 of the cases. They develop from the elements constituting the nerve and are generally schwannomas (80 p. 100). Other tumors are much more exceptional and exhibit wide histological variability. The diagnosis of a tumor of the peripheral nerve must be envisaged for all cases with tumefaction or pain on the path of a nerve exacerbated at percussion. Magnetic resonance imaging is the preferred exploration technique, particularly useful in case of a deep tumor. Preservation of nerve continuity is the underlying goal of the therapeutic strategy, irrespective of the type of tumor. Extricable tumors are to be distinguished from inextricable tumors. Extricable tumors (schwannomas, intranervous lipomas) displace nerve fiber bundles without penetrating into the bundle itself and can thus be resected without interrupting nerve continuity. Prognosis is excellent if no recurrence or degeneration occurs. In case of persistent symptoms, a new exploration may be required to search for other localized tumor(s) unperceived at the first procedure. Inextricable tumors (solitary neurofibromas, hemangiomas of the Schwann sheath, neurofibrolipomas) infiltrate the structural elements of the nerve fibers making complete excision impossible without altering the nerve fibers. Epineurotomy (associated with an interfascicular biopsy for pathology examination) allows decompression and can often provide symptom relief although moderate paresthesia may persist. Patients must be informed of this possibility prior to surgery. Any recent and rapidly evolving modification in the clinical findings is suggestive of recurrence and should be followed by revision exploration. Malignant degeneration has not been observed in solitary tumors to our knowledge. Our own experience with 51 cases is generally in agreement with reports in the literature.

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Mesh:

Year:  2000        PMID: 11148420

Source DB:  PubMed          Journal:  Rev Chir Orthop Reparatrice Appar Mot        ISSN: 0035-1040


  7 in total

1.  A rare cause of chronic sciatic pain: Schwannoma of the sciatic nerve.

Authors:  Abdelkarim Rhanim; Rachid El Zanati; Mustapha Mahfoud; Mohammed Saleh Berrada; Moradh El Yaacoubi
Journal:  J Clin Orthop Trauma       Date:  2013-04-26

2.  [Schwannoma of the sciatic nerve: a case report].

Authors:  Aniss Chagou; Hamza Benameur; Jalal Hassoun; Abdeloihab Jaafar
Journal:  Pan Afr Med J       Date:  2020-11-13

3.  Surgical management of peripheral nerve sheath tumours in children, with special consideration of neurofibromatoses.

Authors:  Julian Zipfel; Meizer Al-Hariri; Isabel Gugel; Karin Haas-Lude; Alexander Grimm; Steven Warmann; Michael Krimmel; Victor-Felix Mautner; Marcos Tatagiba; Martin U Schuhmann
Journal:  Childs Nerv Syst       Date:  2020-06-06       Impact factor: 1.475

4.  Expression of noggin, an antagonist of bone morphogenetic protein, in schwannoma: A possible mechanism.

Authors:  Keiko Kaneko; Chikahisa Higuchi; Norifumi Naka; Hideki Yoshikawa
Journal:  Oncol Lett       Date:  2014-05-12       Impact factor: 2.967

5.  Unusual cause of non-discogenic sciatica: Foraminal lumbar root schwannoma.

Authors:  C Karekezi; K Egu; B O Djoubairou; M Boutarbouch; A El Ouahabi
Journal:  Surg Neurol Int       Date:  2014-07-30

6.  Intraparotid facial nerve plexiform neurofibroma in a child (case report).

Authors:  Adil Lekhbal; Hicham Lyoubi; Omar Wydadi; Anas Bouzbouz; Reda Lah Abada; Sami Rouadi; Mohamed Roubal; Mohamed Mahtar
Journal:  Ann Med Surg (Lond)       Date:  2020-05-08

7.  Median nerve compression in carpal tunnel caused by a giant lipoma.

Authors:  F Fazilleau; T Williams; J Richou; V Sauleau; D Le Nen
Journal:  Case Rep Orthop       Date:  2014-05-04
  7 in total

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