| Literature DB >> 11148064 |
M G Organ1, D Mayhew, J T Cooper, C E Dixon, D J Lavorato, S W Kaldor, M G Siegel.
Abstract
The synthesis of allylic amine libraries derived from olefin templates is described. The two-step, solution phase reaction sequence consists of amination of the template followed by Suzuki coupling and expedited purification via ion exchange chromatography. The methodology has been used to synthesize a 1344-member allylic amine library.Entities:
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Year: 2001 PMID： 11148064 DOI： 10.1021/cc0000601
Source DB: PubMed Journal: J Comb Chem ISSN： 1520-4766