Literature DB >> 11146013

Parental pediatric corticosteroid preferences.

J M Isa1, G K Wong, S S Teraoka, M J Sera, M M Tsushima, L G Yamamoto.   

Abstract

Corticosteroids are often prescribed in the acute care management of asthma. Prednisolone can be administered intramuscularly (IM) or orally in 2 different concentrations. This study evaluated parental preference for three prednisolone preparations based on the route of administration, taste, and volume required. Accompanying adults (AAs) of pediatric patients were interviewed about their preferences based on the 3 factors. Those AAs who passed the health screen (51 of 214) were asked to taste 2 oral prednisolone preparations and reinterviewed about their corticosteroid preferences. Of the 214 AAs, 96% were parents. Of the group, 43% preferred IM corticosteroids whereas 40% preferred oral corticosteroids. Without considering taste as a factor for oral corticosteroids, 94% preferred the more concentrated syrup compared with the less concentrated one. When told that the less concentrated syrup tasted better, 58% preferred the less concentrated/better tasting syrup. After the 51 taste test subcohort subjects tasted the syrups, 96% preferred the less concentrated/ better tasting syrup over the more concentrated/poorer tasting syrup. Taste is more important than volume of administration for this particular corticosteroid comparison. Simply asking parents about their IM/oral and syrup formulation preferences may be the easiest way of optimizing their treatment plan.

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Year:  2001        PMID: 11146013     DOI: 10.1053/ajem.2001.20025

Source DB:  PubMed          Journal:  Am J Emerg Med        ISSN: 0735-6757            Impact factor:   2.469


  2 in total

Review 1.  Methodology Used to Assess Acceptability of Oral Pediatric Medicines: A Systematic Literature Search and Narrative Review.

Authors:  Punam Mistry; Hannah Batchelor
Journal:  Paediatr Drugs       Date:  2017-06       Impact factor: 3.022

2.  Evaluation of patient-reported outcome measurements as a reliable tool to measure acceptability of the taste of paediatric medicines in an inpatient paediatric population.

Authors:  Punam Mistry; Heather Stirling; Claire Callens; James Hodson; Hannah Batchelor
Journal:  BMJ Open       Date:  2018-07-11       Impact factor: 2.692

  2 in total

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