BACKGROUND: Congestive heart failure (CHF) and depression are independently known to result in physical decline and diminished functional capacity in the general population. The prevalence and relationship of depressive symptoms in CHF to physical limitations has not been objectively examined. METHODS AND RESULTS: The Center for Epidemiological Studies Depression Scale (CES-D) was used to ascertain depressive symptoms in 33 elderly ambulatory individuals with CHF. Self-report assessment of functional status, cardiopulmonary exercise testing (CPX), and measurement of energy expenditure by doubly labeled water and Caltrac Accelerometer (Muscle Dynamics, Torrance, CA) were performed. Depressed and nondepressed groups were compared. Forty-two percent of the patients scored in the depressed range (CES-D score of 16 or greater). There were no differences in demographic variables or severity of illness between the depressed and nondepressed patients. Energy expenditure was comparable across groups. Although obtaining similar maximal heart rate and maximal oxygen consumption (VO2max) on CPX, the depressed group showed less exertion on exercise testing with a significantly lower respiratory quotient (P = .017). CONCLUSION: Depressive symptoms were common and unrelated to the severity of CHF. Although depressed individuals tended to report worse physical functioning than nondepressed individuals, objective assessment of energy expenditure was comparable. Depressed patients appear to underestimate their functional ability. Subsequently, inaccurate assessment of functional status may occur.
BACKGROUND:Congestive heart failure (CHF) and depression are independently known to result in physical decline and diminished functional capacity in the general population. The prevalence and relationship of depressive symptoms in CHF to physical limitations has not been objectively examined. METHODS AND RESULTS: The Center for Epidemiological Studies Depression Scale (CES-D) was used to ascertain depressive symptoms in 33 elderly ambulatory individuals with CHF. Self-report assessment of functional status, cardiopulmonary exercise testing (CPX), and measurement of energy expenditure by doubly labeled water and Caltrac Accelerometer (Muscle Dynamics, Torrance, CA) were performed. Depressed and nondepressed groups were compared. Forty-two percent of the patients scored in the depressed range (CES-D score of 16 or greater). There were no differences in demographic variables or severity of illness between the depressed and nondepressed patients. Energy expenditure was comparable across groups. Although obtaining similar maximal heart rate and maximal oxygen consumption (VO2max) on CPX, the depressed group showed less exertion on exercise testing with a significantly lower respiratory quotient (P = .017). CONCLUSION:Depressive symptoms were common and unrelated to the severity of CHF. Although depressed individuals tended to report worse physical functioning than nondepressed individuals, objective assessment of energy expenditure was comparable. Depressedpatients appear to underestimate their functional ability. Subsequently, inaccurate assessment of functional status may occur.
Authors: Michael L Alosco; Mary Beth Spitznagel; Ronald Cohen; Naftali Raz; Lawrence H Sweet; Richard Josephson; Joel Hughes; Jim Rosneck; John Gunstad Journal: Int J Geriatr Psychiatry Date: 2013-09-10 Impact factor: 3.485
Authors: Ranak B Trivedi; James A Blumenthal; Christopher O'Connor; Kirkwood Adams; Alan Hinderliter; Carla Dupree; Kristy Johnson; Andrew Sherwood Journal: J Psychosom Res Date: 2009-10 Impact factor: 3.006
Authors: Michael L Alosco; Mary Beth Spitznagel; Manfred van Dulmen; Naftali Raz; Ronald Cohen; Lawrence H Sweet; Lisa H Colbert; Richard Josephson; Joel Hughes; Jim Rosneck; John Gunstad Journal: J Aging Health Date: 2013-01-31
Authors: Stephen S Gottlieb; Willem J Kop; Stephen J Ellis; Philip Binkley; Jonathan Howlett; Christopher O'Connor; James A Blumenthal; Gerald Fletcher; Ann M Swank; Lawton Cooper Journal: Am J Cardiol Date: 2009-02-28 Impact factor: 2.778
Authors: Michael L Alosco; Mary Beth Spitznagel; Naftali Raz; Ronald Cohen; Lawrence H Sweet; Sarah Garcia; Richard Josephson; Manfred van Dulmen; Joel Hughes; Jim Rosneck; John Gunstad Journal: Psychosom Med Date: 2013-07-19 Impact factor: 4.312