Literature DB >> 11145498

Methadone, ciprofloxacin, and adverse drug reactions.

K Herrlin, M Segerdahl, L L Gustafsson, E Kalso.   

Abstract

Ciprofloxacin, given to a patient successfully treated with methadone for more than 6 years, caused profound sedation, confusion, and respiratory depression. We suggest that this was caused by ciprofloxacin inhibition of CYP1A2 and CYP3A4 activity, two of the cytochrome p450 isozymes involved in the metabolism of methadone.

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Year:  2000        PMID: 11145498     DOI: 10.1016/S0140-6736(00)03409-7

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  14 in total

1.  Interaction between Methadone and Ciprofloxacin.

Authors:  Leslie Samoy; Karen F Shalansky
Journal:  Can J Hosp Pharm       Date:  2010-09

Review 2.  The pharmacological importance of cytochrome CYP3A4 in the palliation of symptoms: review and recommendations for avoiding adverse drug interactions.

Authors:  Abdo Haddad; Mellar Davis; Ruth Lagman
Journal:  Support Care Cancer       Date:  2006-12-01       Impact factor: 3.603

Review 3.  Pharmacologic Treatment of Opioid Use Disorder: a Review of Pharmacotherapy, Adjuncts, and Toxicity.

Authors:  Michael S Toce; Peter R Chai; Michele M Burns; Edward W Boyer
Journal:  J Med Toxicol       Date:  2018-10-30

Review 4.  Interindividual variability of the clinical pharmacokinetics of methadone: implications for the treatment of opioid dependence.

Authors:  Chin B Eap; Thierry Buclin; Pierre Baumann
Journal:  Clin Pharmacokinet       Date:  2002       Impact factor: 6.447

Review 5.  Quinolones: review of psychiatric and neurological adverse reactions.

Authors:  Ana M Tomé; Augusto Filipe
Journal:  Drug Saf       Date:  2011-06-01       Impact factor: 5.606

Review 6.  Methadone: applied pharmacology and use as adjunctive treatment in chronic pain.

Authors:  R Brown; C Kraus; M Fleming; S Reddy
Journal:  Postgrad Med J       Date:  2004-11       Impact factor: 2.401

7.  Pharmacokinetic interaction between zolpidem and ciprofloxacin in healthy volunteers.

Authors:  Laurian Vlase; Adina Popa; Maria Neag; Dana Muntean; Sorin E Leucuţa
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2010-10-05       Impact factor: 2.441

8.  Ciprofloxacin blocked enterohepatic circulation of diclofenac and alleviated NSAID-induced enteropathy in rats partly by inhibiting intestinal β-glucuronidase activity.

Authors:  Ze-Yu Zhong; Bin-Bin Sun; Nan Shu; Qiu-Shi Xie; Xian-Ge Tang; Zhao-Li Ling; Fan Wang; Kai-Jing Zhao; Ping Xu; Mian Zhang; Ying Li; Yang Chen; Li Liu; Lun-Zhu Xia; Xiao-Dong Liu
Journal:  Acta Pharmacol Sin       Date:  2016-05-16       Impact factor: 6.150

9.  Contribution of the activities of CYP3A, CYP2D6, CYP1A2 and other potential covariates to the disposition of methadone in patients undergoing methadone maintenance treatment.

Authors:  Mohammad-Reza Shiran; Martin S Lennard; Mohammad-Zafar Iqbal; Oldwale Lagundoye; Nicholas Seivewright; Geoffrey T Tucker; Amin Rostami-Hodjegan
Journal:  Br J Clin Pharmacol       Date:  2009-01       Impact factor: 4.335

Review 10.  Rational prescription of drugs within similar therapeutic or structural class for gastrointestinal disease treatment: drug metabolism and its related interactions.

Authors:  Quan Zhou; Xiao-Feng Yan; Zhong-Miao Zhang; Wen-Sheng Pan; Su Zeng
Journal:  World J Gastroenterol       Date:  2007-11-14       Impact factor: 5.742

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