Literature DB >> 11145465

Extraosseous epidural IgD myeloma presenting with compression myelopathy.

Y Watanabe1, A Endou, S Ooi, E Matsushima, Y Shimisu, K Nakashima.   

Abstract

An 85-year-old man presented with acute transverse myelopathy: flaccid paraplegia, superficial and deep sensory disturbance below Th6 and loss of urinary sensation. Spinal magnetic resonance image showed an epidural mass compressing the spinal cord at the level of C7 to Th2. Immunoelectrophoresis revealed the presence of immunoglobulin D (IgD)-lambda M protein. Chemotherapy markedly improved both the haematologic aspect and tumor size, but not the motor deficit. In IgD myeloma, extraosseous spreads occur frequently, but extraosseous epidural tumors causing compression myelopathy are relatively rare. To our knowledge, this is the fourth report of cases.

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Year:  2000        PMID: 11145465     DOI: 10.1046/j.1440-1819.2000.00767.x

Source DB:  PubMed          Journal:  Psychiatry Clin Neurosci        ISSN: 1323-1316            Impact factor:   5.188


  2 in total

Review 1.  Solitary spinal extradural plasmacytoma: a case report and literature review.

Authors:  S Tsutsumi; Y Yasumoto; M Ito
Journal:  Clin Neuroradiol       Date:  2012-06-16       Impact factor: 3.649

2.  Solitary extramedullary plasmacytoma of thoracic epidural space presenting with dorsal compressive myelopathy: A case report and review of literature.

Authors:  Amandeep Kumar; Guru Dutt Satyarthee; Mukund Sable; Vaishali Suri; Bhawani S Sharma
Journal:  J Neurosci Rural Pract       Date:  2015 Jul-Sep
  2 in total

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