| Literature DB >> 1114332 |
C Kennedy, M H Des Rosiers, J W Jehle, M Reivich, F Sharpe, L Sokoloff.
Abstract
An enzymatic preparation from human brain converts tryptamine to tryptoline (9H-1,2,3,4-tetrahydropyrido(3,4-b)indole) in the presence of 5-methyltetrahydrofolic acid. Similarly, N-methyltryptamine and 5-hydroxytryptamine yield 1-methyltryptoline and 5-hydroxytryptoline, respectively. Neither in vitro nor in vivo formation of these compounds by human tissues has been described.Entities:
Mesh:
Substances:
Year: 1975 PMID: 1114332 DOI: 10.1126/science.1114332
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728