| Literature DB >> 1114316 |
Abstract
Unilateral cerebrovascular occlusion was produced in heparinized rats within 60 seconds after an injection of sodium arachidonate (in doses exceeding 0.45 milligram per kilogram) into the carotid artery. Electroencephalographic activity over the affected cerebral hemisphere was suppressed, and cerebral blood flow decreased by half. Microscopic examination revealed complete obstruction of the hemispheric microcirculation by platelet aggregates.Entities:
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Year: 1975 PMID: 1114316 DOI: 10.1126/science.1114316
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728