Literature DB >> 11142975

Prehospital blood transfusion versus crystalloid alone in the air medical transport of trauma patients.

M P Sumida1, K Quinn, P L Lewis, Y Jones, D E Barker, D L Ciraulo, V Cowell, S Luk, D Murphy, L Jacobs.   

Abstract

INTRODUCTION: Differences in prehospital resuscitation measures and outcomes of trauma patients transported by two air medical programs were assessed comparing the prehospital administration of crystalloid only (Group A) with the administration of 2 liters of crystalloid followed by blood (Group B).
METHODS: A 1-year retrospective review of flight and hospital records of patients taken to Level I trauma centers by two separate air medical programs was completed. Physiologic variables, total fluids infused, and flight times were compared.
RESULTS: Thirty-one patients (Group A) received crystalloids in flight, and 17 patients received in-flight blood (Group B). No statistical differences were found between the two groups when comparing age, ISS, PS, RTS, GCS, survival, and total fluid volume. Group B had statistically greater mean flight times compared with Group A (P < .05). A difference was demonstrated between groups A and B in pH and HCO3 measurements (P < .05), with Group B presenting in a more acidotic state on admission to the hospital.
CONCLUSION: Patients with lengthy flight times, despite the administration of blood products, presented to the trauma center more acidotic than trauma patients receiving only crystalloid. The true impact of blood products on outcome could not be demonstrated because of statistical differences in flight times between the groups. A multicenter study matching flight times, head injury status, and flight type of assess benefit of prehospital utilization of blood products is warranted.

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Year:  2000        PMID: 11142975     DOI: 10.1016/s1067-991x(00)90007-5

Source DB:  PubMed          Journal:  Air Med J        ISSN: 1067-991X


  9 in total

1.  Pre-trauma center red blood cell transfusion is associated with improved early outcomes in air medical trauma patients.

Authors:  Joshua B Brown; Jason L Sperry; Anisleidy Fombona; Timothy R Billiar; Andrew B Peitzman; Francis X Guyette
Journal:  J Am Coll Surg       Date:  2015-01-24       Impact factor: 6.113

Review 2.  Mortality outcomes in trauma patients undergoing prehospital red blood cell transfusion: a systematic literature review.

Authors:  Gregory S Huang; C Michael Dunham
Journal:  Int J Burns Trauma       Date:  2017-04-15

3.  Pretrauma center red blood cell transfusion is associated with reduced mortality and coagulopathy in severely injured patients with blunt trauma.

Authors:  Joshua B Brown; Mitchell J Cohen; Joseph P Minei; Ronald V Maier; Michaela A West; Timothy R Billiar; Andrew B Peitzman; Ernest E Moore; Joseph Cuschieri; Jason L Sperry
Journal:  Ann Surg       Date:  2015-05       Impact factor: 12.969

4.  Blood Product Supply for a Helicopter Emergency Medical Service.

Authors:  Kathleen Selleng; Marcel Baschin; Berthold Henkel; Gregor Jenichen; Karl-Christian Thies; Marcus Rudolph; Florian Reifferscheid; Jörg Braun; Malte Hannich; Theresa Winter; Klaus Hahnenkamp; Andreas Greinacher
Journal:  Transfus Med Hemother       Date:  2021-10-19       Impact factor: 3.747

5.  Prehospital synergy: Tranexamic acid and blood transfusion in patients at risk for hemorrhage.

Authors:  Andrew-Paul Deeb; Lara Hoteit; Shimena Li; Francis X Guyette; Brian J Eastridge; Raminder Nirula; Gary A Vercruysse; Terence O'Keeffe; Bellal Joseph; Matthew D Neal; Jason L Sperry; Joshua B Brown
Journal:  J Trauma Acute Care Surg       Date:  2022-04-08       Impact factor: 3.697

6.  Protocol for a systematic review of the clinical effectiveness of pre-hospital blood components compared to other resuscitative fluids in patients with major traumatic haemorrhage.

Authors:  Janine Dretzke; Iain M Smith; Robert H James; Mark J Midwinter
Journal:  Syst Rev       Date:  2014-10-24

Review 7.  Prehospital Blood Product Resuscitation for Trauma: A Systematic Review.

Authors:  Iain M Smith; Robert H James; Janine Dretzke; Mark J Midwinter
Journal:  Shock       Date:  2016-07       Impact factor: 3.454

Review 8.  Pre-hospital transfusion of red blood cells. Part 2: A systematic review of treatment effects on outcomes.

Authors:  Elisabeth C van Turenhout; Sebastiaan M Bossers; Stephan A Loer; Georgios F Giannakopoulos; Lothar A Schwarte; Patrick Schober
Journal:  Transfus Med       Date:  2020-01-05       Impact factor: 2.019

9.  Mortality of civilian patients with suspected traumatic haemorrhage receiving pre-hospital transfusion of packed red blood cells compared to pre-hospital crystalloid.

Authors:  J E Griggs; J Jeyanathan; M Joy; M Q Russell; N Durge; D Bootland; S Dunn; E D Sausmarez; G Wareham; A Weaver; R M Lyon
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2018-11-20       Impact factor: 2.953

  9 in total

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