Literature DB >> 11142268

Gamma hydroxybutyric acid (GHB): an increasing trend in drug abuse.

S H Boyce1, K Padgham, L D Miller, J Stevenson.   

Abstract

The use of recreational drugs in society is becoming a widespread problem increasing the workload of all the emergency services. Gamma hydroxybutyric acid (GHB) is one of these, a drug used primarily for its euphoric effect. Toxic effects of ingestion include bradycardia, slow respiration or apnoea, coma and death. We present seven cases, all of which had consumed GHB either alone or in conjunction with other drugs and alcohol. The presentation, clinical features and management of these cases are described. All health care personnel involved in the emergency setting need to know of its existence, toxic effects and initial management with particular reference to airway control and possible assisted ventilation.

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Year:  2000        PMID: 11142268     DOI: 10.1097/00063110-200009000-00003

Source DB:  PubMed          Journal:  Eur J Emerg Med        ISSN: 0969-9546            Impact factor:   2.799


  2 in total

1.  Pathway-specific action of gamma-hydroxybutyric acid in sensory thalamus and its relevance to absence seizures.

Authors:  Nicolas Gervasi; Zohreh Monnier; Pierre Vincent; Daniele Paupardin-Tritsch; Stuart W Hughes; Vincenzo Crunelli; Nathalie Leresche
Journal:  J Neurosci       Date:  2003-12-10       Impact factor: 6.167

2.  Comprehensive Application of Time-of-flight Secondary Ion Mass Spectrometry (TOF-SIMS) for Ionic Imaging and Bio-energetic Analysis of Club Drug-induced Cognitive Deficiency.

Authors:  Su-Chung Youn; Li-You Chen; Ruei-Jen Chiou; Te-Jen Lai; Wen-Chieh Liao; Fu-Der Mai; Hung-Ming Chang
Journal:  Sci Rep       Date:  2015-12-17       Impact factor: 4.379

  2 in total

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