| Literature DB >> 11141107 |
M Iwashima1, Y Matsumoto, H Takahashi, K Iguchi.
Abstract
Seven new marine diterpenoids having a cembrane skeleton were isolated from the Okinawan soft coral Clavularia koellikeri. Their structures were determined based on the results of spectroscopic analysis and chemical conversions. Compound 1 showed cytotoxic activity against human colorectal adenocarcinoma cells (DLD-1, IC(50) 4.2 g/mL) and strong growth inhibition against human T lymphocytic leukemia cells (MOLT-4, IC(50) 0.9 g/mL).Entities:
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Year: 2000 PMID： 11141107 DOI： 10.1021/np000309w
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050