Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Cytotoxic cembrenolides and steroids from the formosan soft coral Sarcophyton crassocaule.

Literature DB >> 11141104

Cytotoxic cembrenolides and steroids from the formosan soft coral Sarcophyton crassocaule.

C Y Duh¹, S K Wang, S G Chung, G C Chou, C F Dai.

Abstract

Three new cytotoxic cembrenolide diterpenes, sarcocrassolide (1), crassolide (2), and 13-acetoxysarcocrassolide (3); a known cytotoxic cembrenolide, denticulatolide (4); and two cytotoxic steroids, (24S)-24-methylcholestane-3beta,5alpha,6beta-triol (5) and 24zeta-methylcholestane-3beta,5alpha,6beta,25-te traol-25-monoacetate (6), have been isolated from the Formosan soft coral Sarcophyton crassocaule. The structures of compounds 1-6 were determined by 1D and 2D spectral analysis.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2000 PMID： 11141104 DOI： 10.1021/np0002381

Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050

Keyword Cloud
Cited

20 in total

1. New lobane and cembrane diterpenes from two comorian soft corals.

Authors: Isabelle Bonnard; Sabina B Jhaumeer-Laulloo; Nataly Bontemps; Bernard Banaigs; Maurice Aknin
Journal: Mar Drugs Date: 2010-02-23 Impact factor: 5.118

2. An investigation into the cytotoxic effects of 13-acetoxysarcocrassolide from the soft coral Sarcophyton crassocaule on bladder cancer cells.

Authors: Ching-Chyuan Su; Jui-Hsin Su; Jen-Jie Lin; Cheng-Chi Chen; Wen-Ing Hwang; Han Hsiang Huang; Yu-Jen Wu
Journal: Mar Drugs Date: 2011-12-13 Impact factor: 6.085

3. Sarcocrassocolides M-O, bioactive cembranoids from the Dongsha Atoll soft coral Sarcophyton crassocaule.

Authors: Wan-Yu Lin; Yi Lu; Bo-Wei Chen; Chiung-Yao Huang; Jui-Hsin Su; Zhi-Hong Wen; Chang-Feng Dai; Yao-Haur Kuo; Jyh-Horng Sheu
Journal: Mar Drugs Date: 2012-03-08 Impact factor: 6.085

4. Capgermacrenes A and B, Bioactive Secondary Metabolites from a Bornean Soft Coral, Capnella sp.

Authors: Chin-Soon Phan; Shean-Yeaw Ng; Eun-A Kim; You-Jin Jeon; Kishneth Palaniveloo; Charles Santhanaraju Vairappan
Journal: Mar Drugs Date: 2015-05-19 Impact factor: 5.118

5. 13-acetoxysarcocrassolide induces apoptosis on human gastric carcinoma cells through mitochondria-related apoptotic pathways: p38/JNK activation and PI3K/AKT suppression.

Authors: Ching-Chyuan Su; Jeff Yi-Fu Chen; Zhong-Hao Din; Jui-Hsin Su; Zih-Yan Yang; Yi-Jen Chen; Robert Y L Wang; Yu-Jen Wu
Journal: Mar Drugs Date: 2014-10-23 Impact factor: 5.118

Review 10. Cytotoxic and cytolytic cnidarian venoms. A review on health implications and possible therapeutic applications.

Authors: Gian Luigi Mariottini; Luigi Pane
Journal: Toxins (Basel) Date: 2013-12-27 Impact factor: 4.546

Cytotoxic cembrenolides and steroids from the formosan soft coral Sarcophyton crassocaule.

1. New lobane and cembrane diterpenes from two comorian soft corals.

2. An investigation into the cytotoxic effects of 13-acetoxysarcocrassolide from the soft coral Sarcophyton crassocaule on bladder cancer cells.

3. Sarcocrassocolides M-O, bioactive cembranoids from the Dongsha Atoll soft coral Sarcophyton crassocaule.

4. Capgermacrenes A and B, Bioactive Secondary Metabolites from a Bornean Soft Coral, Capnella sp.

5. 13-acetoxysarcocrassolide induces apoptosis on human gastric carcinoma cells through mitochondria-related apoptotic pathways: p38/JNK activation and PI3K/AKT suppression.

6. Aquaculture Soft Coral Lobophytum crassum as a Producer of Anti-Proliferative Cembranoids.

7. Immunomodulatory effect of marine cembrane-type diterpenoids on dendritic cells.

8. Bioactive polyoxygenated steroids from the South China sea soft coral, Sarcophyton sp.

9. Sarcophyolides B-E, new cembranoids from the soft coral Sarcophyton elegans.

Review 10. Cytotoxic and cytolytic cnidarian venoms. A review on health implications and possible therapeutic applications.