| Literature DB >> 11140741 |
A M Redman1, J S Johnson, R Dally, S Swartz, H Wild, H Paulsen, Y Caringal, D Gunn, J Renick, M Osterhout, J Kingery-Wood, R A Smith, W Lee, J Dumas, S M Wilhelm, T J Housley, A Bhargava, G E Ranges, A Shrikhande, D Young, M Bombara, W J Scott.
Abstract
Inhibitors of the MAP kinase p38 are potentially useful for the treatment for osteoporosis, arthritis, and other inflammatory diseases. A series of thienyl, furyl, and pyrrolyl ureas has been identified as potent p38 inhibitors, displaying in vitro activity in the nanomolar range.Entities:
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Year: 2001 PMID： 11140741 DOI： 10.1016/s0960-894x(00)00574-6
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823