Literature DB >> 11139135

The isoprostanes: their quantification as an index of oxidant stress status in vivo.

J D Morrow1.   

Abstract

The F2 isoprostanes are a unique series of prostaglandinlike compounds formed in vivo from the free-radical-catalyzed peroxidation of arachidonic acid independent of the cyclooxygenase enzyme. The purpose of this review is to briefly summarize the status of our current knowledge regarding the isoprostanes. Novel aspects related to the biochemistry of isoprostane formation and methods by which these compounds are analyzed are discussed. The utility of measuring F2 isoprostanes as markers of lipid peroxidation in animal models of oxidant stress are then outlined. Finally, examples are provided in which quantification of isoprostanes have illuminated the role of oxidative injury in several human diseases.

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Year:  2000        PMID： 11139135     DOI： 10.1081/dmr-100102340

Source DB:  PubMed          Journal:  Drug Metab Rev        ISSN： 0360-2532            Impact factor:   4.518


  47 in total

Review 1.  Unorthodox routes to prostanoid formation: new twists in cyclooxygenase-initiated pathways.

Authors:  C N Serhan; E Oliw
Journal:  J Clin Invest       Date:  2001-06       Impact factor: 14.808

Review 2.  Urinary biomarkers of oxidative status.

Authors:  Dora Il'yasova; Peter Scarbrough; Ivan Spasojevic
Journal:  Clin Chim Acta       Date:  2012-06-07       Impact factor: 3.786

3.  Urinary F2-isoprostanes, obesity, and weight gain in the IRAS cohort.

Authors:  Dora Il'yasova; Frances Wang; Ivan Spasojevic; Karel Base; Ralph B D'Agostino; Lynne E Wagenknecht
Journal:  Obesity (Silver Spring)       Date:  2011-09-29       Impact factor: 5.002

4.  F2-isoprostanes and Metabolite, and Breast Cancer Risk.

Authors:  Qi Dai; Xiangzhu Zhu
Journal:  N Am J Med Sci (Boston)       Date:  2009-07

5.  Effects of combination tocopherols and alpha lipoic acid therapy on oxidative stress and inflammatory biomarkers in chronic kidney disease.

Authors:  Luis F Ramos; Jane Kane; Ellen McMonagle; Phuong Le; Pingsheng Wu; Ayumi Shintani; Talat Alp Ikizler; Jonathan Himmelfarb
Journal:  J Ren Nutr       Date:  2010-12-24       Impact factor: 3.655

Review 6.  Postprandial lipid oxidation and cardiovascular disease risk.

Authors:  Phyllis E Bowen; Gayatri Borthakur
Journal:  Curr Atheroscler Rep       Date:  2004-11       Impact factor: 5.113

7.  Can urinary excretion rate of 8-isoprostrane and malonaldehyde predict postoperative cognitive dysfunction in aging?

Authors:  Qinghao Cheng; Jiawan Wang; Anshi Wu; Rujin Zhang; Lei Li; Yun Yue
Journal:  Neurol Sci       Date:  2013-02-05       Impact factor: 3.307

Review 8.  Nutritional countermeasures targeting reactive oxygen species in cancer: from mechanisms to biomarkers and clinical evidence.

Authors:  Anatoly Samoylenko; Jubayer Al Hossain; Daniela Mennerich; Sakari Kellokumpu; Jukka Kalervo Hiltunen; Thomas Kietzmann
Journal:  Antioxid Redox Signal       Date:  2013-04-15       Impact factor: 8.401

9.  Role of prostanoid production and receptors in the regulation of retinal endogenous amino acid neurotransmitters by 8-isoprostaglandin E2, ex vivo.

Authors:  Min Zhao; Christopher J Destache; Sunny E Ohia; Catherine A Opere
Journal:  Neurochem Res       Date:  2009-12       Impact factor: 3.996

10.  Exercise training, NADPH oxidase p22phox gene polymorphisms, and hypertension.

Authors:  Deborah L Feairheller; Michael D Brown; Joon-Young Park; Tina E Brinkley; Samar Basu; James M Hagberg; Robert E Ferrell; Nicola M Fenty-Stewart
Journal:  Med Sci Sports Exerc       Date:  2009-07       Impact factor: 5.411
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