| Literature DB >> 11137023 |
M A Wear1, D A Schafer, J A Cooper.
Abstract
Assembly of branched actin filament networks at the leading edge of migrating cells requires stimulation of the Arp2/3 complex by WASp proteins, in concert with the WASp activators Cdc42, PIP(2) and profilin. Network disassembly and debranching appears to be linked to actin-bound ATP hydrolysis as filaments age.Entities:
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Year: 2000 PMID: 11137023 DOI: 10.1016/s0960-9822(00)00845-9
Source DB: PubMed Journal: Curr Biol ISSN: 0960-9822 Impact factor: 10.834