BACKGROUND: Stroke, hypertension and diabetes are common in older Caribbean-born populations in the UK who may be at risk of depression secondary to vascular disease. AIMS: We examined the association between stroke, vascular risk factors and depression in a community-based Caribbean-born population aged 55-75 years. METHOD: Vascular risk factors were identified by interview, examination and blood tests. Depression was categorised using the Geriatric Depression Scale. Disablement was assessed as a potential mediating factor. RESULTS: Physical illness and disablement were strongly associated with depression, independent of disablement. Previous stroke was associated with depression, independent of disablement. No vascular risk factors were associated with depression. CONCLUSIONS: The risk of depression associated with stroke was not explained by disablement. However, the hypothesis that vascular risk factors are important in the genesis of depression was not supported.
BACKGROUND:Stroke, hypertension and diabetes are common in older Caribbean-born populations in the UK who may be at risk of depression secondary to vascular disease. AIMS: We examined the association between stroke, vascular risk factors and depression in a community-based Caribbean-born population aged 55-75 years. METHOD: Vascular risk factors were identified by interview, examination and blood tests. Depression was categorised using the Geriatric Depression Scale. Disablement was assessed as a potential mediating factor. RESULTS: Physical illness and disablement were strongly associated with depression, independent of disablement. Previous stroke was associated with depression, independent of disablement. No vascular risk factors were associated with depression. CONCLUSIONS: The risk of depression associated with stroke was not explained by disablement. However, the hypothesis that vascular risk factors are important in the genesis of depression was not supported.
Authors: Chien-Ti Lee; Jeannie-Marie Leoutsakos; Constantine G Lyketsos; David C Steffens; John C S Breitner; Maria C Norton Journal: Int J Geriatr Psychiatry Date: 2011-12-02 Impact factor: 3.485
Authors: Zia Ul-Haq; Daniel J Smith; Barbara I Nicholl; Breda Cullen; Daniel Martin; Jason M R Gill; Jonathan Evans; Beverly Roberts; Ian J Deary; John Gallacher; Matthew Hotopf; Nick Craddock; Daniel F Mackay; Jill P Pell Journal: BMC Psychiatry Date: 2014-05-26 Impact factor: 3.630