Literature DB >> 11135613

Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics.

M A Kay1, J C Glorioso, L Naldini.   

Abstract

Considered by some to be among the simpler forms of life, viruses represent highly evolved natural vectors for the transfer of foreign genetic information into cells. This attribute has led to extensive attempts to engineer recombinant viral vectors for the delivery of therapeutic genes into diseased tissues. While substantial progress has been made, and some clinical successes are over the horizon, further vector refinement and/or development is required before gene therapy will become standard care for any individual disorder.

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Year:  2001        PMID: 11135613     DOI: 10.1038/83324

Source DB:  PubMed          Journal:  Nat Med        ISSN: 1078-8956            Impact factor:   53.440


  276 in total

1.  In vivo assessment of gene delivery to keratinocytes by lentiviral vectors.

Authors:  Ulrich Kuhn; Atsushi Terunuma; Wolfgang Pfutzner; Ruth Ann Foster; Jonathan C Vogel
Journal:  J Virol       Date:  2002-02       Impact factor: 5.103

Review 2.  Nonviral gene transfer strategies for the vasculature.

Authors:  Jennifer L Young; David A Dean
Journal:  Microcirculation       Date:  2002-01       Impact factor: 2.628

Review 3.  Cardiac gene therapy: from concept to reality.

Authors:  Razmig Garo Kratlian; Roger J Hajjar
Journal:  Curr Heart Fail Rep       Date:  2012-03

4.  A novel pancreatropic coxsackievirus vector expressing glucagon-like peptide 1 reduces hyperglycemia in streptozotocin-treated mice.

Authors:  Meixia Dan; Janet K Chantler
Journal:  J Virol       Date:  2011-09-21       Impact factor: 5.103

5.  Optimization of the transductional efficiency of lentiviral vectors: effect of sera and polycations.

Authors:  Warren Denning; Suvendu Das; Siqi Guo; Jun Xu; John C Kappes; Zdenek Hel
Journal:  Mol Biotechnol       Date:  2013-03       Impact factor: 2.695

6.  Identification of a novel proliferation-inducing determinant using lentiviral expression cloning.

Authors:  Dmitri Chilov; Cornelia Fux; Hana Joch; Martin Fussenegger
Journal:  Nucleic Acids Res       Date:  2003-09-15       Impact factor: 16.971

Review 7.  Nonneurotropic adenovirus: a vector for gene transfer to the brain and gene therapy of neurological disorders.

Authors:  Pedro R Lowenstein; Donata Suwelack; Jinwei Hu; Xianpeng Yuan; Maximiliano Jimenez-Dalmaroni; Shyam Goverdhana; Maria G Castro
Journal:  Int Rev Neurobiol       Date:  2003       Impact factor: 3.230

Review 8.  Use of localised gene transfer to develop new treatment strategies for the salivary component of Sjögren's syndrome.

Authors:  M R Kok; B J Baum; P P Tak; S R Pillemer
Journal:  Ann Rheum Dis       Date:  2003-11       Impact factor: 19.103

9.  Thermodynamic basis for the genome to capsid charge relationship in viral encapsidation.

Authors:  Christina L Ting; Jianzhong Wu; Zhen-Gang Wang
Journal:  Proc Natl Acad Sci U S A       Date:  2011-10-03       Impact factor: 11.205

Review 10.  Physical non-viral gene delivery methods for tissue engineering.

Authors:  Adam J Mellott; M Laird Forrest; Michael S Detamore
Journal:  Ann Biomed Eng       Date:  2012-10-26       Impact factor: 3.934

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