| Literature DB >> 11135607 |
Abstract
Studies on mice lacking the peroxisome proliferator-activated receptor (PPAR) suggest that PPAR ligands reduce lipid accumulation in foamy macrophages, and may target other receptors. These findings warrant an in-depth investigation into the gene regulatory mechanisms of PPAR ligands, which are currently being developed as drugs to treat atherosclerosis and diabetes.Entities:
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Year: 2001 PMID： 11135607 DOI： 10.1038/83301
Source DB: PubMed Journal: Nat Med ISSN： 1078-8956 Impact factor: 53.440