Literature DB >> 11134321

Recombinant expression of lymphocytic choriomeningitis virus strain WE glycoproteins: a single amino acid makes the difference.

W R Beyer1, H Miletic, W Ostertag, D von Laer.   

Abstract

Cytoplasmic vector systems are generally used for expression of lymphocytic choriomeningitis virus (LCMV) proteins. However, we achieved high levels of cell surface glycoproteins using a standard nuclear expression plasmid. Expression was independent of other LCMV proteins but was blocked by a missense mutation within the original LCMV(WE) glycoprotein cDNA.

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Year:  2001        PMID: 11134321      PMCID: PMC114004          DOI: 10.1128/JVI.75.2.1061-1064.2001

Source DB:  PubMed          Journal:  J Virol        ISSN: 0022-538X            Impact factor:   5.103


  19 in total

1.  Vaccination for disease.

Authors:  S Oehen; H Hengartner; R M Zinkernagel
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2.  Anti-viral protection and prevention of lymphocytic choriomeningitis or of the local footpad swelling reaction in mice by immunization with vaccinia-recombinant virus expressing LCMV-WE nucleoprotein or glycoprotein.

Authors:  M Hany; S Oehen; M Schulz; H Hengartner; M Mackett; D H Bishop; H Overton; R M Zinkernagel
Journal:  Eur J Immunol       Date:  1989-03       Impact factor: 5.532

3.  Molecular characterization of the genomic S RNA segment from lymphocytic choriomeningitis virus.

Authors:  P J Southern; M K Singh; Y Riviere; D R Jacoby; M J Buchmeier; M B Oldstone
Journal:  Virology       Date:  1987-03       Impact factor: 3.616

4.  Lymphocytic choriomeningitis virus. VI. Isolation of a glycoprotein mediating neutralization.

Authors:  M Bruns; J Cihak; G Müller; F Lehmann-Grube
Journal:  Virology       Date:  1983-10-15       Impact factor: 3.616

5.  Induction of diabetes is influenced by the infectious virus and local expression of MHC class I and tumor necrosis factor-alpha.

Authors:  P S Ohashi; S Oehen; P Aichele; H Pircher; B Odermatt; P Herrera; Y Higuchi; K Buerki; H Hengartner; R M Zinkernagel
Journal:  J Immunol       Date:  1993-06-01       Impact factor: 5.422

6.  Complete sequence of the S RNA of lymphocytic choriomeningitis virus (WE strain) compared to that of Pichinde arenavirus.

Authors:  V Romanowski; Y Matsuura; D H Bishop
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7.  Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice.

Authors:  P S Ohashi; S Oehen; K Buerki; H Pircher; C T Ohashi; B Odermatt; B Malissen; R M Zinkernagel; H Hengartner
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8.  Protein-protein interactions in lymphocytic choriomeningitis virus.

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9.  Virus-lymphocyte interactions. IV. Molecular characterization of LCMV Armstrong (CTL+) small genomic segment and that of its variant, Clone 13 (CTL-).

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  18 in total

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2.  Endoproteolytic processing of the lymphocytic choriomeningitis virus glycoprotein by the subtilase SKI-1/S1P.

Authors:  Winfried R Beyer; Dennis Pöpplau; Wolfgang Garten; Dorothee von Laer; Oliver Lenz
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10.  Remission of invasive, cancer stem-like glioblastoma xenografts using lentiviral vector-mediated suicide gene therapy.

Authors:  Peter C Huszthy; Tsanan Giroglou; Oleg Tsinkalovsky; Philipp Euskirchen; Kai Ove Skaftnesmo; Rolf Bjerkvig; Dorothee von Laer; Hrvoje Miletic
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