Literature DB >> 11134059

The Role of presenilins in gamma-secretase activity.

M S Wolfe1, C Haass.   

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Year:  2000        PMID: 11134059     DOI: 10.1074/jbc.R000026200

Source DB:  PubMed          Journal:  J Biol Chem        ISSN: 0021-9258            Impact factor:   5.157


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  26 in total

1.  The intramembrane cleavage site of the amyloid precursor protein depends on the length of its transmembrane domain.

Authors:  Stefan F Lichtenthaler; Dirk Beher; Heike S Grimm; Rong Wang; Mark S Shearman; Colin L Masters; Konrad Beyreuther
Journal:  Proc Natl Acad Sci U S A       Date:  2002-01-22       Impact factor: 11.205

2.  A physiologic signaling role for the gamma -secretase-derived intracellular fragment of APP.

Authors:  Malcolm A Leissring; M Paul Murphy; Tonya R Mead; Yama Akbari; Michael C Sugarman; Mehrdad Jannatipour; Brigitte Anliker; Ulrike Müller; Paul Saftig; Bart De Strooper; Michael S Wolfe; Todd E Golde; Frank M LaFerla
Journal:  Proc Natl Acad Sci U S A       Date:  2002-03-26       Impact factor: 11.205

3.  The presenilins turned inside out: implications for their structures and functions.

Authors:  Nazneen N Dewji; Dante Valdez; S J Singer
Journal:  Proc Natl Acad Sci U S A       Date:  2004-01-19       Impact factor: 11.205

4.  The initial substrate-binding site of gamma-secretase is located on presenilin near the active site.

Authors:  Anna Y Kornilova; Frédéric Bihel; Chittaranjan Das; Michael S Wolfe
Journal:  Proc Natl Acad Sci U S A       Date:  2005-02-18       Impact factor: 11.205

5.  An early specific cell-cell interaction occurs in the production of beta-amyloid in cell cultures.

Authors:  Nazneen N Dewji; Debashis Mukhopadhyay; S Jonathan Singer
Journal:  Proc Natl Acad Sci U S A       Date:  2006-01-23       Impact factor: 11.205

6.  Presenilin-based genetic screens in Drosophila melanogaster identify novel notch pathway modifiers.

Authors:  Matt B Mahoney; Annette L Parks; David A Ruddy; Stanley Y K Tiong; Hanife Esengil; Alexander C Phan; Panos Philandrinos; Christopher G Winter; Runa Chatterjee; Kari Huppert; William W Fisher; Lynn L'Archeveque; Felipa A Mapa; Wendy Woo; Michael C Ellis; Daniel Curtis
Journal:  Genetics       Date:  2006-01-16       Impact factor: 4.562

Review 7.  Guinea pigs as a nontransgenic model for APP processing in vitro and in vivo.

Authors:  Mike Beck; Volker Bigl; Steffen Rossner
Journal:  Neurochem Res       Date:  2003-04       Impact factor: 3.996

8.  Disruption of a novel member of a sodium/hydrogen exchanger family and DOCK3 is associated with an attention deficit hyperactivity disorder-like phenotype.

Authors:  M G de Silva; K Elliott; H-H Dahl; E Fitzpatrick; S Wilcox; M Delatycki; R Williamson; D Efron; M Lynch; S Forrest
Journal:  J Med Genet       Date:  2003-10       Impact factor: 6.318

9.  Wnt5a controls Notch1 signaling through CaMKII-mediated degradation of the SMRT corepressor protein.

Authors:  Eun-Jung Ann; Hwa-Young Kim; Mi-Sun Seo; Jung-Soon Mo; Mi-Yeon Kim; Ji-Hye Yoon; Ji-Seon Ahn; Hee-Sae Park
Journal:  J Biol Chem       Date:  2012-08-10       Impact factor: 5.157

10.  Two novel spliced presenilin 2 transcripts in human lymphocyte with oxidant stress and brain.

Authors:  Nobuyuki Takahashi; Shingo Kariya; Makito Hirano; Satoshi Ueno
Journal:  Mol Cell Biochem       Date:  2003-10       Impact factor: 3.396

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