Literature DB >> 11133080

Novel antifungals based on 4-substituted imidazole: solid-phase synthesis of substituted aryl sulfonamides towards optimization of in vitro activity.

A K Saha1, L Liu, P Marichal, F Odds.   

Abstract

The in vitro activity of novel 4-substituted imidazole antifungals was optimized by solid-phase chemistry and parallel synthesis. Potent yeast-selective as well as broad-spectrum antifungal compounds (32 and 20) were discovered.

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Year:  2000        PMID： 11133080     DOI： 10.1016/s0960-894x(00)00551-5

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  1 in total

1.  Synthesis of 2-acyloxycyclohexylsulfonamides and evaluation on their fungicidal activity.

Authors:  Xinghai Li; Zining Cui; Xiaoyuan Chen; Decai Wu; Zhiqiu Qi; Mingshan Ji
Journal:  Int J Mol Sci       Date:  2013-11-14       Impact factor: 5.923
  1 in total

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