Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Interaction of soluble fibroblast surface antigen with fribrinogen and fibrin.

Literature DB >> 1113066

Interaction of soluble fibroblast surface antigen with fribrinogen and fibrin.

Abstract

A cell-type specific glycoprotein antigen (SFA) from fibroblast surface appears in human plasma and serum. The amount of SFA in serum was reduced if the blood coagulation clot was removed at a low temperature. SFA could be bound to Sepharose-conjugated fibrinogen and to fibrin powder at 0 degrees C and was subsequently released when the temperature was elevated to plus 37 degrees C. This procedure resulted in a 10-fold enrichment of SFA relative to other serum proteins. SFA was found to be concentrated in the cryoprecipitate fraction of human plasma and was copurified with the cold insoluble globulin (CIG) with procedures published for the purification of the latter component. SFA/CIG is not soluble at low temperatures as such and its appearance in the cryoprecipitate fraction of plasma is likely to be due to its affinity to cryofibrinogen evident from these experiments. The biological significance of the interaction of fibroblast surface SFA moleculres with fibrin(ogen) is not known.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 1975 PMID： 1113066 PMCID： PMC2190538 DOI： 10.1084/jem.141.2.497

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

13 in total

1. Protein measurement with the Folin phenol reagent.

Authors: O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal: J Biol Chem Date: 1951-11 Impact factor: 5.157

2. Alteration of cell-surface proteins by viral transformation and by proteolysis.

Authors: R O Hynes
Journal: Proc Natl Acad Sci U S A Date: 1973-11 Impact factor: 11.205

3. Changes in a surface-labelled galactoprotein and in glycolipid concentrations in cells transformed by a temperature-sensitive polyoma virus mutant.

Authors: C G Gahmberg; D Kiehn; S Hakomori
Journal: Nature Date: 1974-03-29 Impact factor: 49.962

4. Disappearance of a major cell-type specific surface glycoprotein antigen (SF) after transformation of fibroblasts by Rous sarcoma virus.

Authors: A Vaheri; E Ruoslahti
Journal: Int J Cancer Date: 1974-05-15 Impact factor: 7.396

5. The cold-insoluble globulin of human plasma. I. Purification, primary characterization, and relationship to fibrinogen and other cold-insoluble fraction components.

Authors: M W Mosesson; R A Umfleet
Journal: J Biol Chem Date: 1970-11-10 Impact factor: 5.157

6. Novel human serum protein from fibroblast plasma membrane.

Authors: E Ruoslahti; A Vaheri
Journal: Nature Date: 1974-04-26 Impact factor: 49.962

7. Chemical coupling of proteins to agarose.

Authors: J Porath; R Axen; S Ernback
Journal: Nature Date: 1967-09-30 Impact factor: 49.962

8. Distribution of fibroblast surface antigen: association with fibrillar structures of normal cells and loss upon viral transformation.

Authors: J Wartiovaara; E Linder; E Ruoslahti; A Vaheri
Journal: J Exp Med Date: 1974-12-01 Impact factor: 14.307

9. Fibrinolysis associated with oncogenic transformation. Requirement of plasminogen for correlated changes in cellular morphology, colony formation in agar, and cell migration.

Authors: L Ossowski; J P Quigley; G M Kellerman; E Reich
Journal: J Exp Med Date: 1973-11-01 Impact factor: 14.307

10. An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. II. Mammalian fibroblast cultures transformed by DNA and RNA tumor viruses.

Authors: L Ossowski; J C Unkeless; A Tobia; J P Quigley; D B Rifkin; E Reich
Journal: J Exp Med Date: 1973-01-01 Impact factor: 14.307

72 in total

1. Comparison of the fibrin-binding activities in the N- and C-termini of fibronectin.

Authors: A A Rostagno; J E Schwarzbauer; L I Gold
Journal: Biochem J Date: 1999-03-01 Impact factor: 3.857

2. Effect of fibronectin on the Crithidia luciliae test for anti-double-stranded DNA antibodies.

Authors: K E Herbert; E Jeffery; D L Scott
Journal: Ann Rheum Dis Date: 1990-09 Impact factor: 19.103

3. Changes in cellular glycoproteins after transformation: identification of specific glycoproteins and antigens in sodium dodecyl sulfate gels.

Authors: K Burridge
Journal: Proc Natl Acad Sci U S A Date: 1976-12 Impact factor: 11.205

Interaction of soluble fibroblast surface antigen with fribrinogen and fibrin.

1. Protein measurement with the Folin phenol reagent.

2. Alteration of cell-surface proteins by viral transformation and by proteolysis.

3. Changes in a surface-labelled galactoprotein and in glycolipid concentrations in cells transformed by a temperature-sensitive polyoma virus mutant.

4. Disappearance of a major cell-type specific surface glycoprotein antigen (SF) after transformation of fibroblasts by Rous sarcoma virus.

5. The cold-insoluble globulin of human plasma. I. Purification, primary characterization, and relationship to fibrinogen and other cold-insoluble fraction components.

6. Novel human serum protein from fibroblast plasma membrane.

7. Chemical coupling of proteins to agarose.

8. Distribution of fibroblast surface antigen: association with fibrillar structures of normal cells and loss upon viral transformation.

9. Fibrinolysis associated with oncogenic transformation. Requirement of plasminogen for correlated changes in cellular morphology, colony formation in agar, and cell migration.

10. An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. II. Mammalian fibroblast cultures transformed by DNA and RNA tumor viruses.

1. Comparison of the fibrin-binding activities in the N- and C-termini of fibronectin.

2. Effect of fibronectin on the Crithidia luciliae test for anti-double-stranded DNA antibodies.

3. Changes in cellular glycoproteins after transformation: identification of specific glycoproteins and antigens in sodium dodecyl sulfate gels.

4. Products of cultured neuroglial cells: II. The production of fibronectin by C6 glioma cells.

5. Fibronectin of the chorioretinal interface in the monkey: immunohistochemical and immunoelectron microscopic studies.

6. Surface glycoproteins of resting and activated human T lymphocytes.

7. Plasma fibronectin in normal subjects and in various disease states.

8. Purification of fibronectin from human plasma by affinity chromatography under non-denaturing conditions.

9. Ganglioside inhibition of fibronectin-mediated cell adhesion to collagen.

10. Immunological studies of human placentae: identification and distribution of proteins in immature chorionic villi.