Literature DB >> 11130529

Ep-CAM overexpression in breast cancer as a predictor of survival.

G Gastl, G Spizzo, P Obrist, M Dünser, G Mikuz.   

Abstract

The epithelial glycoprotein Ep-CAM is overexpressed in colon cancer and breast cancer. We assessed the frequency and prognostic significance of Ep-CAM in tissue specimens from 205 patients with invasive breast cancer, by immunohistochemical staining with a monoclonal antibody specific for the Ep-CAM antigen. Ep-CAM overexpression was found in 35.6% of samples and was associated with poor disease-free and overall survival.

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Year:  2000        PMID： 11130529     DOI： 10.1016/S0140-6736(00)03312-2

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  97 in total

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