| Literature DB >> 11128637 |
A K Bence1, D T Rogers, D R Worthen, M Fu, J M Littleton, P A Crooks.
Abstract
As part of a drug discovery program using high-throughput radioligand-binding assays, aminoanthraquinones were identified as potential modulators of N-methyl-D-aspartate (NMDA) receptor function. Aminoanthraquinones may represent a novel class of polyamine binding site ligands with a unique pharmacophore and may facilitate the rational design of novel NMDA-receptor modulators.Entities:
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Year: 2000 PMID： 11128637 DOI： 10.1016/s0960-894x(00)00530-8
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823