Literature DB >> 11124171

Streptokinase versus alteplase and other treatments for acute and delayed thrombolysis of blood stains in clothing.

C K Pager1.   

Abstract

OBJECTIVE: To assess the usefulness of heparin, alteplase, and streptokinase in removing blood stains.
DESIGN: Randomised controlled trial.
SETTING: Hospital laundry.
INTERVENTIONS: Blood stains were allocated to treatment with alteplase, streptokinase, heparin, a commercial enzymatic stain remover, or no treatment at all after three or seven hours and then washed in hot or cold water two hours later.
RESULTS: Both hot water and early treatment were strongly associated with improved stain removal. All four treatments were associated with a worse outcome than no treatment at all, although for streptokinase this trend did not reach significance. The commercial stain remover gave the worst results of all treatments tested.
CONCLUSIONS: Contrary to popular wisdom, hot water is much more effective than cold in removing blood stains. Methodologically rigorous research and evidence based principles are needed within the laundry industry, and the role of thrombolytic drugs should be assessed further.

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Year:  2000        PMID: 11124171      PMCID: PMC27558          DOI: 10.1136/bmj.321.7276.1554

Source DB:  PubMed          Journal:  BMJ        ISSN: 0959-8138


  3 in total

Review 1.  Update in thrombolytic therapy.

Authors:  W Hacke; P Ringleb; R Stingele
Journal:  Rev Neurol (Paris)       Date:  1999       Impact factor: 2.607

Review 2.  [How did the results of ECASS II influence clinical practice of treatment of acute stroke].

Authors:  W Hacke; P Ringleb; R Stingele
Journal:  Rev Neurol       Date:  1999 Oct 1-15       Impact factor: 0.870

3.  Comparative efficacy of a two-hour regimen of streptokinase versus alteplase in acute massive pulmonary embolism: immediate clinical and hemodynamic outcome and one-year follow-up.

Authors:  N Meneveau; F Schiele; D Metz; B Valette; P Attali; A Vuillemenot; G Grollier; J Elaerts; J M Mossard; J F Viel; J P Bassand
Journal:  J Am Coll Cardiol       Date:  1998-04       Impact factor: 24.094

  3 in total

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