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Literature DB >> 11123018

Cytokines and the immunopathology of the spondyloarthropathies.

Abstract

In contrast to rheumatoid arthritis (RA), the triggering antigens are known in reactive arthritis (ReA) and Lyme arthritis. Thus, in these arthritides the antigen-specific T-cell response can be investigated in much detail and lessons possibly learned for other spondyloarthropathies (SpA) such as ankylosing spondylitis (AS) where T cells may well also play an important role in the pathogenesis. This article focusses on the immunopathology of the SpA, ReA, and AS with special reference to T cells and cytokines.

Entities: Disease

Mesh：

Substances：
Cytokines

Year: 1999 PMID： 11123018 DOI： 10.1007/s11926-999-0028-y

Source DB: PubMed Journal: Curr Rheumatol Rep ISSN： 1523-3774 Impact factor: 4.592

116 in total

1. Tumor necrosis factor gene polymorphisms in ankylosing spondylitis.

Authors: A Fraile; A Nieto; Y Beraún; J Vinasco; L Matarán; J Martín
Journal: Tissue Antigens Date: 1998-04

2. A genome-wide screen for susceptibility loci in ankylosing spondylitis.

Authors: M A Brown; K D Pile; L G Kennedy; D Campbell; L Andrew; R March; J L Shatford; D E Weeks; A Calin; B P Wordsworth
Journal: Arthritis Rheum Date: 1998-04

Review 3. T-cell reactivity to human HSP60 in oligo-articular juvenile chronic arthritis is associated with a favorable prognosis and the generation of regulatory cytokines in the inflamed joint.

Authors: A B Prakken; M J van Hoeij; W Kuis; A Kavelaars; C J Heynen; E Scholtens; I M de Kleer; G T Rijkers; W van Eden
Journal: Immunol Lett Date: 1997-06-01 Impact factor: 3.685

4. Nested polymerase chain reaction strategy simultaneously targeting DNA sequences of multiple bacterial species in inflammatory joint diseases. I. Screening of synovial fluid samples of patients with spondyloarthropathies and other arthritides.

Authors: J Braun; M Tuszewski; U Eggens; A Mertz; C Schauer-Petrowskaja; E Döring; S Laitko; A Distler; J Sieper; S Ehlers
Journal: J Rheumatol Date: 1997-06 Impact factor: 4.666

5. Nested polymerase chain reaction strategy simultaneously targeting DNA sequences of multiple bacterial species in inflammatory joint diseases. II. Examination of sacroiliac and knee joint biopsies of patients with spondyloarthropathies and other arthritides.

Authors: J Braun; M Tuszewski; S Ehlers; J Häberle; M Bollow; U Eggens; A Distler; J Sieper
Journal: J Rheumatol Date: 1997-06 Impact factor: 4.666

6. Stimulation of suppressive T cell responses by human but not bacterial 60-kD heat-shock protein in synovial fluid of patients with rheumatoid arthritis.

Authors: J A van Roon; W van Eden; J L van Roy; F J Lafeber; J W Bijlsma
Journal: J Clin Invest Date: 1997-07-15 Impact factor: 14.808

Cytokines and the immunopathology of the spondyloarthropathies.

1. Tumor necrosis factor gene polymorphisms in ankylosing spondylitis.

2. A genome-wide screen for susceptibility loci in ankylosing spondylitis.

Review 3. T-cell reactivity to human HSP60 in oligo-articular juvenile chronic arthritis is associated with a favorable prognosis and the generation of regulatory cytokines in the inflamed joint.

4. Nested polymerase chain reaction strategy simultaneously targeting DNA sequences of multiple bacterial species in inflammatory joint diseases. I. Screening of synovial fluid samples of patients with spondyloarthropathies and other arthritides.

5. Nested polymerase chain reaction strategy simultaneously targeting DNA sequences of multiple bacterial species in inflammatory joint diseases. II. Examination of sacroiliac and knee joint biopsies of patients with spondyloarthropathies and other arthritides.

6. Stimulation of suppressive T cell responses by human but not bacterial 60-kD heat-shock protein in synovial fluid of patients with rheumatoid arthritis.

7. Association between polymorphisms at the human IL-10 locus and systemic lupus erythematosus.

8. Tumour necrosis factor microsatellites in reactive arthritis.

9. Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation.

10. Cellular immunity to cartilage proteoglycans: relevance to the pathogenesis of ankylosing spondylitis.

Review 1. Pathways of cell activation in spondyloarthropathies.