Literature DB >> 11122850

Genetic polymorphism and cancer risk.

M L Clapper1.   

Abstract

Inter-individual variability in carcinogen metabolism has been attributed in part to the polymorphic expression of several phase I and II detoxification enzymes. The role of these genetic polymorphisms in cancer susceptibility has been most extensively evaluated for isozymes of cytochrome P450 (CYP1A1, CYP2D6, and CYP2E1), N-acetyltransferase (NAT1 and NAT2), glutathione S-transferase (GSTM1, GSTT1, and GSTP1), microsomal epoxide hydrolase, and NAD(P)H:quinone oxidoreductase. Our understanding of the genetic basis of cancer risk has been enhanced most recently by establishment of genotype-phenotype correlations in humans and identification of numerous diverse factors, both genetic and environmental, that can modify risk.

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Year:  2000        PMID： 11122850     DOI： 10.1007/s11912-000-0075-z

Source DB:  PubMed          Journal:  Curr Oncol Rep        ISSN： 1523-3790            Impact factor:   5.075


  39 in total

1.  The role of ethnicity in cancer susceptibility gene polymorphisms: the example of CYP1A1.

Authors:  S Garte
Journal:  Carcinogenesis       Date:  1998-08       Impact factor: 4.944

2.  GSTM1, GSTP1, CYP1A1 and CYP2D6 polymorphisms in lung cancer patients from an environmentally polluted region of Poland: correlation with lung DNA adduct levels.

Authors:  D Butkiewicz; K J Cole; D H Phillips; C C Harris; M Chorazy
Journal:  Eur J Cancer Prev       Date:  1999-08       Impact factor: 2.497

3.  A case-control study of cytochrome P450 1A1, glutathione S-transferase M1, cigarette smoking and lung cancer susceptibility (Massachusetts, United States)

Authors:  M Garcia-Closas; K T Kelsey; J K Wiencke; X Xu; J C Wain; D C Christiani
Journal:  Cancer Causes Control       Date:  1997-07       Impact factor: 2.506

4.  Glutathione S-transferase GSTM1, GSTM3, GSTP1 and GSTT1 genotypes and the risk of smoking-related oral and pharyngeal cancers.

Authors:  N Jourenkova-Mironova; A Voho; C Bouchardy; H Wikman; P Dayer; S Benhamou; A Hirvonen
Journal:  Int J Cancer       Date:  1999-03-31       Impact factor: 7.396

5.  Human glutathione S-transferase P1 polymorphism and susceptibility to smoking related epithelial cancer; oral, lung, gastric, colorectal and urothelial cancer.

Authors:  T Katoh; S Kaneko; S Takasawa; N Nagata; H Inatomi; K Ikemura; H Itoh; T Matsumoto; T Kawamoto; D A Bell
Journal:  Pharmacogenetics       Date:  1999-04

Review 6.  P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

Authors:  D R Nelson; L Koymans; T Kamataki; J J Stegeman; R Feyereisen; D J Waxman; M R Waterman; O Gotoh; M J Coon; R W Estabrook; I C Gunsalus; D W Nebert
Journal:  Pharmacogenetics       Date:  1996-02

7.  Induction of pulmonary CYP1A1 by nicotine.

Authors:  M M Iba; H Scholl; J Fung; P E Thomas; J Alam
Journal:  Xenobiotica       Date:  1998-09       Impact factor: 1.908

8.  Cytochrome P450 1A1 MspI polymorphism and urinary 1-hydroxypyrene concentrations in coke-oven workers.

Authors:  M T Wu; S L Huang; C K Ho; Y F Yeh; D C Christiani
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  1998-09       Impact factor: 4.254

9.  Combined effect of polymorphic GST genes on individual susceptibility to lung cancer.

Authors:  S T Saarikoski; A Voho; M Reinikainen; S Anttila; A Karjalainen; C Malaveille; H Vainio; K Husgafvel-Pursiainen; A Hirvonen
Journal:  Int J Cancer       Date:  1998-08-12       Impact factor: 7.396

10.  Microsomal epoxide hydrolase gene polymorphism and susceptibility to colon cancer.

Authors:  D J Harrison; A L Hubbard; J MacMillan; A H Wyllie; C A Smith
Journal:  Br J Cancer       Date:  1999-01       Impact factor: 7.640
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  8 in total

Review 1.  Cytochrome P450 humanised mice.

Authors:  Frank J Gonzalez
Journal:  Hum Genomics       Date:  2004-05       Impact factor: 4.639

2.  Role of glutathione-S-transferase and codon 72 of P53 genotypes in epithelial ovarian cancer patients.

Authors:  Elaine Cristina Morari; Andre Bacellar Costa Lima; Natassia Elena Bufalo; Janaina Luisa Leite; Fabiana Granja; Laura Sterian Ward
Journal:  J Cancer Res Clin Oncol       Date:  2006-05-19       Impact factor: 4.553

3.  High resolution genome-wide analysis of chromosomal alterations in Burkitt's lymphoma.

Authors:  Saloua Toujani; Philippe Dessen; Nathalie Ithzar; Gisèle Danglot; Catherine Richon; Yegor Vassetzky; Thomas Robert; Vladimir Lazar; Jacques Bosq; Lydie Da Costa; Christine Pérot; Vincent Ribrag; Catherine Patte; Jöelle Wiels; Alain Bernheim
Journal:  PLoS One       Date:  2009-09-17       Impact factor: 3.240

4.  Endogenous DNA damage and testicular germ cell tumors.

Authors:  M B Cook; A J Sigurdson; I M Jones; C B Thomas; B I Graubard; L Korde; M H Greene; K A McGlynn
Journal:  Int J Androl       Date:  2008-07-24

5.  Polymorphisms of glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) in ovarian cancer risk.

Authors:  Ying Jin; Zengping Hao
Journal:  Tumour Biol       Date:  2014-02-15

6.  Cooperation of the inducible nitric oxide synthase and cytochrome P450 1A1 in mediating lung inflammation and mutagenicity induced by diesel exhaust particles.

Authors:  Hongwen Zhao; Mark W Barger; Joseph K H Ma; Vincent Castranova; Jane Y C Ma
Journal:  Environ Health Perspect       Date:  2006-08       Impact factor: 9.031

7.  Frequencies of 23 functionally significant variant alleles related with metabolism of antineoplastic drugs in the chilean population: comparison with caucasian and asian populations.

Authors:  Angela Roco; Luis Quiñones; José A G Agúndez; Elena García-Martín; Valentina Squicciarini; Carla Miranda; Joselyn Garay; Nancy Farfán; Iván Saavedra; Dante Cáceres; Carol Ibarra; Nelson Varela
Journal:  Front Genet       Date:  2012-11-02       Impact factor: 4.599

8.  Comparative study and meta-analysis of meta-analysis studies for the correlation of genomic markers with early cancer detection.

Authors:  Zoi Lanara; Efstathia Giannopoulou; Marta Fullen; Evangelos Kostantinopoulos; Jean-Christophe Nebel; Haralabos P Kalofonos; George P Patrinos; Cristiana Pavlidis
Journal:  Hum Genomics       Date:  2013-06-05       Impact factor: 4.639
  8 in total

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