Literature DB >> 11122724

Probucol.

K D Pfuetze1, C A Dujovne.   

Abstract

The purpose of this review article is twofold. It seeks to present an overview of research studies conducted on the many effects of probucol, and it demonstrates the interest in pursuing studies on probucol"s multiple specific actions and its future as a therapeutic agent. Within this article, the results of animal studies, experimental human studies, and clinical human studies are detailed, as is information on toxicology studies and on the side effects of the drug.

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Year:  2000        PMID： 11122724     DOI： 10.1007/s11883-000-0094-0

Source DB:  PubMed          Journal:  Curr Atheroscler Rep        ISSN： 1523-3804            Impact factor:   5.967


  38 in total

1.  Anti-ulcer effects of antioxidants: effect of probucol.

Authors:  M Ito; Y Suzuki; M Ishihara; Y Suzuki
Journal:  Eur J Pharmacol       Date:  1998-08-07       Impact factor: 4.432

2.  Interstitial fibrosis in hypercholesterolemic rats: role of oxidation, matrix synthesis, and proteolytic cascades.

Authors:  A A Eddy
Journal:  Kidney Int       Date:  1998-05       Impact factor: 10.612

3.  Asymmetric dimethylarginine (ADMA): a novel risk factor for endothelial dysfunction: its role in hypercholesterolemia.

Authors:  R H Böger; S M Bode-Böger; A Szuba; P S Tsao; J R Chan; O Tangphao; T F Blaschke; J P Cooke
Journal:  Circulation       Date:  1998-11-03       Impact factor: 29.690

4.  ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree.

Authors:  Y Nakashima; A S Plump; E W Raines; J L Breslow; R Ross
Journal:  Arterioscler Thromb       Date:  1994-01

5.  Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia.

Authors:  T Kita; Y Nagano; M Yokode; K Ishii; N Kume; A Ooshima; H Yoshida; C Kawai
Journal:  Proc Natl Acad Sci U S A       Date:  1987-08       Impact factor: 11.205

6.  Probucol inhibits oxidized-low density lipoprotein-induced adhesion of monocytes to endothelial cells by reducing P-selectin synthesis in vitro.

Authors:  L X Li; J X Chen; D F Liao; L Yu
Journal:  Endothelium       Date:  1998

7.  The effects of LPS and probucol on interleukin 1 (IL-1) and platelet-derived growth factor (PDGF) gene expression in the human monocytic cell line U-937.

Authors:  S R Li; L Forster; E Anggård; G Ferns
Journal:  Biochim Biophys Acta       Date:  1994-02-22

8.  Probucol enhances cholesterol efflux from cultured human skin fibroblasts.

Authors:  R B Goldberg; A Mendez
Journal:  Am J Cardiol       Date:  1988-07-25       Impact factor: 2.778

9.  Influence of probucol on enhanced LDL oxidation after fish oil treatment of hypertriglyceridemic patients.

Authors:  S Lussier-Cacan; S Dubreuil-Quidoz; G Roederer; N Leboeuf; L Boulet; G C de Langavant; J Davignon; M Naruszewicz
Journal:  Arterioscler Thromb       Date:  1993-12

10.  Increased levels of messenger ribonucleic acid for apolipoprotein E in the spleen of probucol-treated rabbits.

Authors:  H Aburatani; A Matsumoto; T Kodama; F Takaku; C Fukazawa; H Itakura
Journal:  Am J Cardiol       Date:  1988-07-25       Impact factor: 2.778
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  6 in total

Review 1.  Clinical pharmacokinetics of antioxidants and their impact on systemic oxidative stress.

Authors:  Edzard Schwedhelm; Renke Maas; Raphael Troost; Rainer H Böger
Journal:  Clin Pharmacokinet       Date:  2003       Impact factor: 6.447

2.  Probucol prevents early coronary heart disease and death in the high-density lipoprotein receptor SR-BI/apolipoprotein E double knockout mouse.

Authors:  Anne Braun; Songwen Zhang; Helena E Miettinen; Shamsah Ebrahim; Teresa M Holm; Eliza Vasile; Mark J Post; Danita M Yoerger; Michael H Picard; Joshua L Krieger; Nancy C Andrews; Michael Simons; Monty Krieger
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-27       Impact factor: 11.205

3.  The Jeremiah Metzger Lecture. Pathogenesis of atherosclerosis: redox as a unifying mechanism.

Authors:  R Wayne Alexander
Journal:  Trans Am Clin Climatol Assoc       Date:  2003

Review 4.  A bumpy and winding but right path to domestic drug-eluting coronary stents.

Authors:  Jae Yeong Cho; Youngkeun Ahn; Myung Ho Jeong
Journal:  Korean Circ J       Date:  2013-10       Impact factor: 3.243

5.  Cysteine-Rich Whey Protein Isolate (CR-WPI) Ameliorates Erectile Dysfunction by Diminishing Oxidative Stress via DDAH/ADMA/NOS Pathway.

Authors:  Kefan Li; Aiyun Zhu; Jimmy Gutman; Qiang Fu; Shuai Liu
Journal:  Oxid Med Cell Longev       Date:  2022-03-21       Impact factor: 6.543

6.  Antidepressant Effects of Probucol on Early-Symptomatic YAC128 Transgenic Mice for Huntington's Disease.

Authors:  Cristine de Paula Nascimento-Castro; Ana Claudia Wink; Victor Silva da Fônseca; Claudia Daniele Bianco; Elisa C Winkelmann-Duarte; Marcelo Farina; Ana Lúcia S Rodrigues; Joana Gil-Mohapel; Andreza Fabro de Bem; Patricia S Brocardo
Journal:  Neural Plast       Date:  2018-08-14       Impact factor: 3.599
  6 in total

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