Literature DB >> 11122714

Antioxidants and coronary artery disease.

A L Catapano1, E Tragni.   

Abstract

The protective role of antioxidants in experimental models of atherosclerosis is only partially confirmed by studies in man. Observational and epidemiologic data, as well as randomized trials failed to provide clear cut indications, because of mixed results on the protective role of antioxidants against cardiovascular diseases. In spite of the lack of a general consensus, recent data reinforce the concept that a regular intake of antioxidants present in food limits the progression of atherosclerosis. When it will be possible to monitor the efficacy of any antioxidant therapy with validated markers of oxidation, the potential influence of vitamins and antioxidants on coronary artery disease may eventually be resolved.

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Year:  1999        PMID: 11122714     DOI: 10.1007/s11883-999-0036-4

Source DB:  PubMed          Journal:  Curr Atheroscler Rep        ISSN: 1523-3804            Impact factor:   5.967


  73 in total

Review 1.  Polyphenolic flavonoids inhibit macrophage-mediated oxidation of LDL and attenuate atherogenesis.

Authors:  M Aviram; B Fuhrman
Journal:  Atherosclerosis       Date:  1998-04       Impact factor: 5.162

2.  Susceptibility of LDL to oxidative stress in obstructive sleep apnea.

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Journal:  Sleep       Date:  1998-05-01       Impact factor: 5.849

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Journal:  Lancet       Date:  1996-03-23       Impact factor: 79.321

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Journal:  N Engl J Med       Date:  1997-08-07       Impact factor: 91.245

5.  Relation between intake of flavonoids and risk for coronary heart disease in male health professionals.

Authors:  E B Rimm; M B Katan; A Ascherio; M J Stampfer; W C Willett
Journal:  Ann Intern Med       Date:  1996-09-01       Impact factor: 25.391

6.  Effect of lercanidipine and its (R)-enantiomer on atherosclerotic lesions induced in hypercholesterolemic rabbits.

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Journal:  Br J Pharmacol       Date:  1998-12       Impact factor: 8.739

7.  A primary prevention trial using nutritional doses of antioxidant vitamins and minerals in cardiovascular diseases and cancers in a general population: the SU.VI.MAX study--design, methods, and participant characteristics. SUpplementation en VItamines et Minéraux AntioXydants.

Authors:  S Hercberg; P Preziosi; S Briançon; P Galan; I Triol; D Malvy; A M Roussel; A Favier
Journal:  Control Clin Trials       Date:  1998-08

8.  Nitric oxide deficiency, leukocyte activation, and resultant ischemia are crucial to the pathogenesis of diabetic retinopathy/neuropathy--preventive potential of antioxidants, essential fatty acids, chromium, ginkgolides, and pentoxifylline.

Authors:  M F McCarty
Journal:  Med Hypotheses       Date:  1998-05       Impact factor: 1.538

9.  Effects of beta-blockers on the concentration and oxidizability of plasma lipids.

Authors:  S B Dimmitt; P D Williams; K D Croft; L J Beilin
Journal:  Clin Sci (Lond)       Date:  1998-06       Impact factor: 6.124

Review 10.  The potential role of antioxidant vitamins in preventing cardiovascular diseases and cancers.

Authors:  S Hercberg; P Galan; P Preziosi; M J Alfarez; C Vazquez
Journal:  Nutrition       Date:  1998-06       Impact factor: 4.008

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