Literature DB >> 11121575

New windows on the mechanism of action of K(ATP) channel openers.

F M Ashcroft1, F M Gribble.   

Abstract

K(ATP) channel openers are a diverse group of drugs with a wide range of potential therapeutic uses. Their molecular targets, the K(ATP) channels, exhibit tissue-specific responses because they possess different types of regulatory sulfonylurea receptor subunits. It is well recognized that complex interactions occur between K(ATP) channel openers and nucleotides, but the cloning of the K(ATP) channel has introduced a new dimension to the study of these events and has furthered our understanding of the molecular basis of the action of K(ATP) channel openers.

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Year:  2000        PMID： 11121575     DOI： 10.1016/s0165-6147(00)01563-7

Source DB:  PubMed          Journal:  Trends Pharmacol Sci        ISSN： 0165-6147            Impact factor:   14.819


  42 in total

1.  Cellular remodeling in heart failure disrupts K(ATP) channel-dependent stress tolerance.

Authors:  Denice M Hodgson; Leonid V Zingman; Garvan C Kane; Carmen Perez-Terzic; Martin Bienengraeber; Cevher Ozcan; Richard J Gumina; Darko Pucar; Fergus O'Coclain; Douglas L Mann; Alexey E Alekseev; Andre Terzic
Journal:  EMBO J       Date:  2003-04-15       Impact factor: 11.598

2.  Binding and effect of K ATP channel openers in the absence of Mg2+.

Authors:  Ulrich Russ; Ulf Lange; Cornelia Löffler-Walz; Annette Hambrock; Ulrich Quast
Journal:  Br J Pharmacol       Date:  2003-05       Impact factor: 8.739

3.  Analysis of the differential modulation of sulphonylurea block of beta-cell and cardiac ATP-sensitive K+ (K(ATP)) channels by Mg-nucleotides.

Authors:  Frank Reimann; Michael Dabrowski; Phillippa Jones; Fiona M Gribble; Frances M Ashcroft
Journal:  J Physiol       Date:  2003-01-10       Impact factor: 5.182

Review 4.  Sulphonylurea action revisited: the post-cloning era.

Authors:  F M Gribble; F Reimann
Journal:  Diabetologia       Date:  2003-06-18       Impact factor: 10.122

Review 5.  Muscle KATP channels: recent insights to energy sensing and myoprotection.

Authors:  Thomas P Flagg; Decha Enkvetchakul; Joseph C Koster; Colin G Nichols
Journal:  Physiol Rev       Date:  2010-07       Impact factor: 37.312

6.  3-D structural and functional characterization of the purified KATP channel complex Kir6.2-SUR1.

Authors:  Michael V Mikhailov; Jeff D Campbell; Heidi de Wet; Kenju Shimomura; Brittany Zadek; Richard F Collins; Mark S P Sansom; Robert C Ford; Frances M Ashcroft
Journal:  EMBO J       Date:  2005-11-24       Impact factor: 11.598

Review 7.  ATP-sensitive potassium channelopathies: focus on insulin secretion.

Authors:  Frances M Ashcroft
Journal:  J Clin Invest       Date:  2005-08       Impact factor: 14.808

Review 8.  ATP-sensitive K+ channel channel/enzyme multimer: metabolic gating in the heart.

Authors:  Alexey E Alekseev; Denice M Hodgson; Amy B Karger; Sungjo Park; Leonid V Zingman; Andre Terzic
Journal:  J Mol Cell Cardiol       Date:  2005-04-14       Impact factor: 5.000

9.  Regulation of cardiac ATP-sensitive potassium channel surface expression by calcium/calmodulin-dependent protein kinase II.

Authors:  Ana Sierra; Zhiyong Zhu; Nicolas Sapay; Vikas Sharotri; Crystal F Kline; Elizabeth D Luczak; Ekaterina Subbotina; Asipu Sivaprasadarao; Peter M Snyder; Peter J Mohler; Mark E Anderson; Michel Vivaudou; Leonid V Zingman; Denice M Hodgson-Zingman
Journal:  J Biol Chem       Date:  2012-12-06       Impact factor: 5.157

10.  Cocaine inhibits cromakalim-activated K+ currents in follicle-enclosed Xenopus oocytes.

Authors:  Murat Oz; Irina Zakharova; Meral Dinc; Toni Shippenberg
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2003-12-03       Impact factor: 3.000
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