Literature DB >> 11120992

Genomic rearrangement of the mec regulator region mediated by insertion of IS431 in methicillin-resistant staphylococci.

N Kobayashi1, M M Alam, S Urasawa.   

Abstract

Genomic diversification of the mec regulator region mediated by IS431 was investigated for clinical isolates of methicillin-resistant staphylococci. A single rearranged form of the mecR1 gene due to IS431 insertion was detected in the three staphylococcal species, while another type of mecR1 truncation with IS431 and an IS431 located downstream of mecI were found only in Staphylococcus haemolyticus. Genetic differentiation of IS431 and staphylococcal isolates suggested transmission of mecDNA with IS431-mediated rearrangement among different staphylococcal species.

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Year:  2001        PMID： 11120992      PMCID： PMC90287          DOI： 10.1128/AAC.45.1.335-338.2001

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  22 in total

1.  Molecular cloning and nucleotide sequence determination of the regulator region of mecA gene in methicillin-resistant Staphylococcus aureus (MRSA).

Authors:  K Hiramatsu; K Asada; E Suzuki; K Okonogi; T Yokota
Journal:  FEBS Lett       Date:  1992-02-24       Impact factor: 4.124

2.  Complete nucleotide sequence of IS431mec in Staphylococcus aureus.

Authors:  L Barberis-Maino; C Ryffel; F H Kayser; B Berger-Bächi
Journal:  Nucleic Acids Res       Date:  1990-09-25       Impact factor: 16.971

Review 3.  Antimicrobial resistance of Staphylococcus aureus: genetic basis.

Authors:  B R Lyon; R Skurray
Journal:  Microbiol Rev       Date:  1987-03

4.  Distribution of insertion sequence-like element IS1272 and its position relative to methicillin resistance genes in clinically important Staphylococci.

Authors:  N Kobayashi; S Urasawa; N Uehara; N Watanabe
Journal:  Antimicrob Agents Chemother       Date:  1999-11       Impact factor: 5.191

5.  Evolution of an inducible penicillin-target protein in methicillin-resistant Staphylococcus aureus by gene fusion.

Authors:  M D Song; M Wachi; M Doi; F Ishino; M Matsuhashi
Journal:  FEBS Lett       Date:  1987-08-31       Impact factor: 4.124

6.  IS431, a staphylococcal insertion sequence-like element related to IS26 from Proteus vulgaris.

Authors:  L Barberis-Maino; B Berger-Bächi; H Weber; W D Beck; F H Kayser
Journal:  Gene       Date:  1987       Impact factor: 3.688

7.  Analysis of genomic diversity within the Xr-region of the protein A gene in clinical isolates of Staphylococcus aureus.

Authors:  N Kobayashi; S Urasawa; N Uehara; N Watanabe
Journal:  Epidemiol Infect       Date:  1999-04       Impact factor: 2.451

8.  Value of molecular epidemiologic analysis in a nosocomial methicillin-resistant Staphylococcus aureus outbreak.

Authors:  F C Fang; M McClelland; D G Guiney; M M Jackson; A I Hartstein; V H Morthland; C E Davis; D C McPherson; J Welsh
Journal:  JAMA       Date:  1993-09-15       Impact factor: 56.272

9.  Distribution of mec regulator genes in methicillin-resistant Staphylococcus clinical strains.

Authors:  E Suzuki; K Kuwahara-Arai; J F Richardson; K Hiramatsu
Journal:  Antimicrob Agents Chemother       Date:  1993-06       Impact factor: 5.191

10.  Comparison of phage typing and DNA fingerprinting by polymerase chain reaction for discrimination of methicillin-resistant Staphylococcus aureus strains.

Authors:  A van Belkum; R Bax; P Peerbooms; W H Goessens; N van Leeuwen; W G Quint
Journal:  J Clin Microbiol       Date:  1993-04       Impact factor: 5.948
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2.  Characterization of Staphylococcus aureus isolates with a partial or complete absence of staphylococcal cassette chromosome elements.

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Journal:  J Clin Microbiol       Date:  2010-07-28       Impact factor: 5.948

3.  Diversity of staphylococcal cassette chromosome mec structures in methicillin-resistant Staphylococcus epidermidis and Staphylococcus haemolyticus strains among outpatients from four countries.

Authors:  Etienne Ruppé; François Barbier; Yasmine Mesli; Aminata Maiga; Radu Cojocaru; Mokhtar Benkhalfat; Samia Benchouk; Hafida Hassaine; Ibrahim Maiga; Amadou Diallo; Abdel Karim Koumaré; Kalilou Ouattara; Sambou Soumaré; Jean-Baptiste Dufourcq; Chhor Nareth; Jean-Louis Sarthou; Antoine Andremont; Raymond Ruimy
Journal:  Antimicrob Agents Chemother       Date:  2008-11-10       Impact factor: 5.191

4.  A potential role of transposon IS431 in the loss of mecA gene.

Authors:  Aihua Wang; Kai Zhou; Yang Liu; Liang Yang; Qin Zhang; Jing Guan; Nanshan Zhong; Chao Zhuo
Journal:  Sci Rep       Date:  2017-01-25       Impact factor: 4.379

5.  Characterizing a Novel Staphylococcal Cassette Chromosome mec with a Composite Structure from a Clinical Strain of Staphylococcus hominis, C34847.

Authors:  Jo-Ann McClure; John M Conly; Kunyan Zhang
Journal:  Antimicrob Agents Chemother       Date:  2021-08-09       Impact factor: 5.191
  5 in total

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