Literature DB >> 11120335

Follicular lymphoma with trisomy 18 and over-expression of BCL2 in the absence of t(14;18)(q32;q21).

K F Wong1, J K Chan.   

Abstract

A 66-year-old female who presented with cervical lymphadenopathy and splenomegaly was found to have large B-cell lymphoma on lymph node biopsy. However, trephine biopsy revealed involvement of the marrow by follicular lymphoma, and cytogenetic study showed an abnormal clone with 47,XX,+18.

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Year:  2000        PMID： 11120335     DOI： 10.1016/s0165-4608(00)00301-0

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN： 0165-4608


  2 in total

1.  B-cell lymphomas with concurrent IGH-BCL2 and MYC rearrangements are aggressive neoplasms with clinical and pathologic features distinct from Burkitt lymphoma and diffuse large B-cell lymphoma.

Authors:  Matija Snuderl; Olga K Kolman; Yi-Bin Chen; Jessie J Hsu; Adam M Ackerman; Paola Dal Cin; Judith A Ferry; Nancy Lee Harris; Robert P Hasserjian; Lawrence R Zukerberg; Jeremy S Abramson; Ephraim P Hochberg; Hang Lee; Alfred I Lee; Christiana E Toomey; Aliyah R Sohani
Journal:  Am J Surg Pathol       Date:  2010-03       Impact factor: 6.394

2.  Follicular lymphoma with trisomy 18 exhibiting loss of BCL-2 expression on transformation to a large cell lymphoma.

Authors:  Noraidah Masir; Roland Ventura; Margaret Jones; Teresa Marafioti; David Y Mason; Jens Samol
Journal:  J Clin Pathol       Date:  2006-12-20       Impact factor: 3.411
  2 in total

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