Z M Al-Karaawi1, V S Lucas, M Gelbier, G J Roberts. 1. Department of Paediatric Dentistry, Eastman Dental Institute, University College London, 256 Gray's Inn Road, London WC1X8LD, UK.
Abstract
OBJECTIVE: To estimate the cumulative exposure to bacteraemia from dental procedures currently recommended for antibiotic prophylaxis and compare this with cumulative exposure from dental procedures not recommended for prophylaxis. DESIGN: Retrospective analysis. SETTING: University and teaching hospital maxillofacial and dental department. PATIENTS: 136 children with severe congenital cardiac disease attending for dental treatment between 1993 and 1998 and for whom full records were available. Each dental procedure was tallied. MAIN OUTCOME MEASURES: Cumulative exposure per annum to "non-prophylaxis procedures"; cumulative exposure per annum to "prophylaxis procedures". RESULTS: Cumulative exposure to bacteraemia from prophylaxis procedures was not significantly greater than from non-prophylaxis procedures. CONCLUSIONS: The data raise important questions about the appropriateness of current guidelines for antibiotic prophylaxis of bacterial endocarditis.
OBJECTIVE: To estimate the cumulative exposure to bacteraemia from dental procedures currently recommended for antibiotic prophylaxis and compare this with cumulative exposure from dental procedures not recommended for prophylaxis. DESIGN: Retrospective analysis. SETTING: University and teaching hospital maxillofacial and dental department. PATIENTS: 136 children with severe congenital cardiac disease attending for dental treatment between 1993 and 1998 and for whom full records were available. Each dental procedure was tallied. MAIN OUTCOME MEASURES: Cumulative exposure per annum to "non-prophylaxis procedures"; cumulative exposure per annum to "prophylaxis procedures". RESULTS: Cumulative exposure to bacteraemia from prophylaxis procedures was not significantly greater than from non-prophylaxis procedures. CONCLUSIONS: The data raise important questions about the appropriateness of current guidelines for antibiotic prophylaxis of bacterial endocarditis.
Authors: A S Dajani; K A Taubert; W Wilson; A F Bolger; A Bayer; P Ferrieri; M H Gewitz; S T Shulman; S Nouri; J W Newburger; C Hutto; T J Pallasch; T W Gage; M E Levison; G Peter; G Zuccaro Journal: JAMA Date: 1997-06-11 Impact factor: 56.272
Authors: Samantha J Rutherford; Anne-Marie Glenny; Graham Roberts; Lee Hooper; Helen V Worthington Journal: Cochrane Database Syst Rev Date: 2022-05-10