| Literature DB >> 11117313 |
A Falshaw1, J B Hart, P C Tyler.
Abstract
The 1D and 1L enantiomers of 1,2-anhydro-myo-inositol (conduritol B epoxide) were synthesised from 1D-pinitol and 1L-quebrachitol, respectively, and their activities were compared in selected glycosidase inhibition assays. The 1D enantiomer was found to be the active isomer, functioning as an irreversible inhibitor of sweet almond beta-D-glucosidase. Neither isomer was active against the alpha-D-glucosidase from Bacillus stearothermophilus or the beta-D-galactosidase from Aspergillus oryzae.Entities:
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Year: 2000 PMID： 11117313 DOI： 10.1016/s0008-6215(00)00192-0
Source DB: PubMed Journal: Carbohydr Res ISSN： 0008-6215 Impact factor: 2.104