Literature DB >> 11116185

The regulation of protein function by multisite phosphorylation--a 25 year update.

P Cohen1.   

Abstract

The phosphorylation of a protein can alter its behaviour in almost every conceivable way. These include modulation of its intrinsic biological activity, subcellular location, half-life and docking with other proteins. 'Multisite phosphorylation can enable several such effects to operate in the same protein. It can also determine the extent and duration of a response and is the key to signal integration.

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Year:  2000        PMID: 11116185     DOI: 10.1016/s0968-0004(00)01712-6

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN: 0968-0004            Impact factor:   13.807


  347 in total

1.  Protein kinase C phosphorylation of purified Na,K-ATPase: C-terminal phosphorylation sites at the alpha- and gamma-subunits close to the inner face of the plasma membrane.

Authors:  Yasser A Mahmmoud; Flemming Cornelius
Journal:  Biophys J       Date:  2002-04       Impact factor: 4.033

2.  Increased phospholipase A2 activity with phosphorylation of peroxiredoxin 6 requires a conformational change in the protein.

Authors:  Hamidur Rahaman; Suiping Zhou; Chandra Dodia; Sheldon I Feinstein; Shaohui Huang; David Speicher; Aron B Fisher
Journal:  Biochemistry       Date:  2012-06-29       Impact factor: 3.162

3.  Comprehensive and reproducible phosphopeptide enrichment using iron immobilized metal ion affinity chromatography (Fe-IMAC) columns.

Authors:  Benjamin Ruprecht; Heiner Koch; Guillaume Medard; Max Mundt; Bernhard Kuster; Simone Lemeer
Journal:  Mol Cell Proteomics       Date:  2014-11-13       Impact factor: 5.911

4.  Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression [corrected].

Authors:  Yingchun Wang; Jonathan A Kelber; Hop S Tran Cao; Greg T Cantin; Rui Lin; Wei Wang; Sharmeela Kaushal; Jeanne M Bristow; Thomas S Edgington; Robert M Hoffman; Michael Bouvet; John R Yates; Richard L Klemke
Journal:  Proc Natl Acad Sci U S A       Date:  2010-06-01       Impact factor: 11.205

5.  A mechanism for the evolution of phosphorylation sites.

Authors:  Samuel M Pearlman; Zach Serber; James E Ferrell
Journal:  Cell       Date:  2011-11-11       Impact factor: 41.582

6.  Equilibrium denaturation studies of the Escherichia coli factor for inversion stimulation: implications for in vivo function.

Authors:  Sarah A Hobart; Sergey Ilin; Daniel F Moriarty; Robert Osuna; Wilfredo Colón
Journal:  Protein Sci       Date:  2002-07       Impact factor: 6.725

Review 7.  Protein kinase CK2: structure, regulation and role in cellular decisions of life and death.

Authors:  David W Litchfield
Journal:  Biochem J       Date:  2003-01-01       Impact factor: 3.857

8.  A phosphomimetic mutation at threonine-57 abolishes transactivation activity and alters nuclear localization pattern of human pregnane x receptor.

Authors:  Satyanarayana R Pondugula; Cynthia Brimer-Cline; Jing Wu; Erin G Schuetz; Rakesh K Tyagi; Taosheng Chen
Journal:  Drug Metab Dispos       Date:  2009-01-26       Impact factor: 3.922

9.  Identification of Kinase-substrate Pairs Using High Throughput Screening.

Authors:  Courtney Reeks; Robert A Screaton
Journal:  J Vis Exp       Date:  2015-08-29       Impact factor: 1.355

10.  Comparison of MS(2)-only, MSA, and MS(2)/MS(3) methodologies for phosphopeptide identification.

Authors:  Peter J Ulintz; Anastasia K Yocum; Bernd Bodenmiller; Ruedi Aebersold; Philip C Andrews; Alexey I Nesvizhskii
Journal:  J Proteome Res       Date:  2009-02       Impact factor: 4.466

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