Literature DB >> 1111486

Pilocarpine toxicity. Effects on the rabbit corneal endothelium.

W H Coles.   

Abstract

The effects of pilocarpine on the healthy rabbit corneal endothelium were studied by in vitro perfusion, photography, and electron microscopy. The toxicity of endothelial cells to pilocarpine was doserelated. Photography showed shrinkage of cells exposed to pilocarpine. The most striking ultrastructure changes were margination of nuclear heterochromatin and cytoplasmic vacuolation.

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Year:  1975        PMID: 1111486     DOI: 10.1001/archopht.1975.01010020040007

Source DB:  PubMed          Journal:  Arch Ophthalmol        ISSN: 0003-9950


  2 in total

Review 1.  Effects of common topical antiglaucoma medications on the ocular surface, eyelids and periorbital tissue.

Authors:  J Javier Servat; C Robert Bernardino
Journal:  Drugs Aging       Date:  2011-04-01       Impact factor: 3.923

2.  Effects of intraocular miotics on cultured bovine corneal endothelium.

Authors:  J L Jay; M MacDonald
Journal:  Br J Ophthalmol       Date:  1978-12       Impact factor: 4.638

  2 in total

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