Literature DB >> 11114772

Silent hydronephrosis/pyonephrosis due to upper urinary tract calculi in spinal cord injury patients.

S Vaidyanathan1, G Singh, B M Soni, P Hughes, J W Watt, S Dundas, P Sett, K F Parsons.   

Abstract

STUDY
DESIGN: A study of four patients with spinal cord injury (SCI) in whom a diagnosis of hydronephrosis or pyonephrosis was delayed since these patients did not manifest the traditional signs and symptoms.
OBJECTIVES: To learn from these cases as to what steps should be taken to prevent any delay in the diagnosis and treatment of hydronephrosis/pyonephrosis in SCI patients.
SETTING: Regional Spinal Injuries Centre, Southport, UK.
METHODS: A retrospective review of cases of hydronephrosis or pyonephrosis due to renal/ ureteric calculus in SCI patients between 1994 and 1999, in whom there was a delay in diagnosis.
RESULTS: A T-5 paraplegic patient had two episodes of urinary tract infection (UTI) which were successfully treated with antibiotics. When he developed UTI again, an intravenous urography (IVU) was performed. The IVU revealed a non-visualised kidney and a renal pelvic calculus. In a T-6 paraplegic patient, the classical symptom of flank pain was absent, and the symptoms of sweating and increased spasms were attributed to a syrinx. A routine IVU showed non-visualisation of the left kidney with a stone impacted in the pelviureteric junction. In two tetraplegic patients, an obstructed kidney became infected, and there was a delay in the diagnosis of pyonephrosis. The clinician's attention was focused on a co-existent, serious, infective pathology elsewhere. The primary focus of sepsis was chest infection in one patient and a deep pressure sore in the other. The former patient succumbed to chest infection and autopsy revealed pyonephrosis with an abscess between the left kidney and left hemidiaphragm and xanthogranulomatous inflammation of perinephric fatty tissue. In the latter patient, an abdominal X-ray did not reveal any calculus but computerised axial tomography showed the presence of renal and ureteric calculi.
CONCLUSIONS: The symptoms of hydronephrosis may be bizarre and non-specific in SCI patients. The symptoms include feeling unwell, abdominal discomfort, increased spasms, and autonomic dysreflexia. Physicians should be aware of the serious import of these symptoms in SCI patients.

Entities:  

Mesh:

Year:  2000        PMID: 11114772     DOI: 10.1038/sj.sc.3101053

Source DB:  PubMed          Journal:  Spinal Cord        ISSN: 1362-4393            Impact factor:   2.772


  6 in total

1.  Unilateral ureteric stone associated with gross hydronephrosis and kidney shrinkage: a cadaveric report.

Authors:  Omid Iravani; Ern-Wei Tay; Boon-Huat Bay; Yee-Kong Ng
Journal:  Anat Cell Biol       Date:  2014-12-23

2.  Managing the urinary tract in spinal cord injury.

Authors:  Simon C W Harrison
Journal:  Indian J Urol       Date:  2010-04

3.  Unpredicted spontaneous extrusion of a renal calculus in an adult male with spina bifida and paraplegia: report of a misdiagnosis. Measures to be taken to reduce urological errors in spinal cord injury patients.

Authors:  S Vaidyanathan; P L Hughes; B M Soni; G Singh; P Mansour; P Sett
Journal:  BMC Urol       Date:  2001-12-20       Impact factor: 2.264

4.  Beyond broken spines-what the radiologist needs to know about late complications of spinal cord injury.

Authors:  Erin Capps; Ken F Linnau; Deborah A Crane
Journal:  Insights Imaging       Date:  2014-12-11

5.  Problems in early diagnosis of bladder cancer in a spinal cord injury patient: report of a case of simultaneous production of granulocyte colony stimulating factor and parathyroid hormone-related protein by squamous cell carcinoma of urinary bladder.

Authors:  Subramanian Vaidyanathan; Paul Mansour; Munehisa Ueno; Kazuto Yamazaki; Meenu Wadhwa; Bakul M Soni; Gurpreet Singh; Peter L Hughes; Ian D Watson; Pradipkumar Sett
Journal:  BMC Urol       Date:  2002-08-30       Impact factor: 2.264

6.  Bladder stones - red herring for resurgence of spasticity in a spinal cord injury patient with implantation of Medtronic Synchromed pump for intrathecal delivery of baclofen - a case report.

Authors:  Subramanian Vaidyanathan; Bakul M Soni; Tun Oo; Peter L Hughes; Gurpreet Singh; John W H Watt; Pradipkumar Sett
Journal:  BMC Urol       Date:  2003-03-25       Impact factor: 2.264

  6 in total

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