| Literature DB >> 11114505 |
E Fan1, E A Merritt, C L Verlinde, W G Hol.
Abstract
High-resolution crystal structures of AB(5) toxins in their native form or in complex with a variety of ligands have led to the structure-based design and discovery of inhibitors targeting different areas of the toxins. The most significant progress is the development of highly potent multivalent ligands that block binding of the toxins to their receptors.Mesh：
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Year: 2000 PMID： 11114505 DOI： 10.1016/s0959-440x(00)00152-4
Source DB: PubMed Journal: Curr Opin Struct Biol ISSN： 0959-440X Impact factor: 6.809