Literature DB >> 11114423

Natural antibodies and complement link innate and acquired immunity.

A F Ochsenbein1, R M Zinkernagel.   

Abstract

Natural or spontaneous antibodies are an essential part of the first line of defense against hematogenically spreading infections, including viruses. These antibodies target virus-antibody complexes and complement to the spleen. This prevents infections from reaching vital organs and enhances neutralizing antibody responses, particularly when the antibody is bound to a highly repetitive antigen.

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Year:  2000        PMID: 11114423     DOI: 10.1016/s0167-5699(00)01754-0

Source DB:  PubMed          Journal:  Immunol Today        ISSN: 0167-5699


  118 in total

1.  Splenic immunity and atherosclerosis: a glimpse into a novel paradigm?

Authors:  Joseph L Witztum
Journal:  J Clin Invest       Date:  2002-03       Impact factor: 14.808

2.  Polyreactive antigen-binding B (PAB-) cells are widely distributed and the PAB population consists of both B-1+ and B-1- phenotypes.

Authors:  Z-H Zhou; A L Notkins
Journal:  Clin Exp Immunol       Date:  2004-07       Impact factor: 4.330

3.  Identification of a specific self-reactive IgM antibody that initiates intestinal ischemia/reperfusion injury.

Authors:  Ming Zhang; William G Austen; Isaac Chiu; Elisabeth M Alicot; Rachel Hung; Minghe Ma; Nicola Verna; Min Xu; Herbert B Hechtman; Francis D Moore; Michael C Carroll
Journal:  Proc Natl Acad Sci U S A       Date:  2004-03-03       Impact factor: 11.205

4.  Maternal antibody persistence: a neglected life-history trait with implications from albatross conservation to comparative immunology.

Authors:  R Garnier; R Ramos; V Staszewski; T Militão; E Lobato; J González-Solís; T Boulinier
Journal:  Proc Biol Sci       Date:  2011-12-21       Impact factor: 5.349

5.  Effects of early developmental conditions on innate immunity are only evident under favourable adult conditions in zebra finches.

Authors:  Greet De Coster; Simon Verhulst; Egbert Koetsier; Liesbeth De Neve; Michael Briga; Luc Lens
Journal:  Naturwissenschaften       Date:  2011-11-12

6.  Sex-specific variation in brown-headed cowbird immunity following acute stress: a mechanistic approach.

Authors:  Loren Merrill; Frédéric Angelier; Adrian L O'Loghlen; Stephen I Rothstein; John C Wingfield
Journal:  Oecologia       Date:  2012-03-01       Impact factor: 3.225

Review 7.  Toll-like receptors and B-cell receptors synergize to induce immunoglobulin class-switch DNA recombination: relevance to microbial antibody responses.

Authors:  Egest J Pone; Hong Zan; Jingsong Zhang; Ahmed Al-Qahtani; Zhenming Xu; Paolo Casali
Journal:  Crit Rev Immunol       Date:  2010       Impact factor: 2.214

8.  West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H.

Authors:  Kyung Min Chung; M Kathryn Liszewski; Grant Nybakken; Alan E Davis; R Reid Townsend; Daved H Fremont; John P Atkinson; Michael S Diamond
Journal:  Proc Natl Acad Sci U S A       Date:  2006-11-28       Impact factor: 11.205

9.  Are there differences in immune function between continental and insular birds?

Authors:  Kevin D Matson
Journal:  Proc Biol Sci       Date:  2006-09-22       Impact factor: 5.349

10.  High natural antibody titers of indigenous chickens are related with increased hazard in confinement.

Authors:  E Wondmeneh; J A M Van Arendonk; E H Van der Waaij; B J Ducro; H K Parmentier
Journal:  Poult Sci       Date:  2015-04-23       Impact factor: 3.352

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