Literature DB >> 11112621

Enantioselective allyltitanation. Efficient synthesis of the C1-C14 polyol subunit of amphotericin B.

S BouzBouz1, J Cossy.   

Abstract

[structure] An efficient synthesis of the C(1)-C(14) fragment of amphotericin B is described. This synthesis is based on the formation of syn-1,3-diols from enantioselective allyltitanation of unprotected beta-hydroxyaldehydes.

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Year:  2000        PMID： 11112621     DOI： 10.1021/ol0063914

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Modular Approach to pseudo-Neoclerodanes as Designer κ-Opioid Ligands.

Authors:  Alexander M Sherwood; Samuel E Williamson; Rachel S Crowley; Logan M Abbott; Victor W Day; Thomas E Prisinzano
Journal:  Org Lett       Date:  2017-09-14       Impact factor: 6.005

Review 2.  A brief history of antibiotics and select advances in their synthesis.

Authors:  Kyriacos C Nicolaou; Stephan Rigol
Journal:  J Antibiot (Tokyo)       Date:  2017-07-05       Impact factor: 2.649

3.  1,n-glycols as dialdehyde equivalents in iridium-catalyzed enantioselective carbonyl allylation and iterative two-directional assembly of 1,3-polyols.

Authors:  Yu Lu; In Su Kim; Abbas Hassan; David J Del Valle; Michael J Krische
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

Review 4.  Chemical syntheses of the salvinorin chemotype of KOR agonist.

Authors:  Sarah J Hill; Aurélien U C M Brion; Ryan A Shenvi
Journal:  Nat Prod Rep       Date:  2020-11-18       Impact factor: 13.423
  4 in total

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