Literature DB >> 11112609

Preparation of new anti-tubulin ligands through a dual-mode, addition-elimination reaction to a bromo-substituted alpha, beta-unsaturated sulfoxide.

Z Chen1, V P Mocharla, J M Farmer, G R Pettit, E Hamel, K G Pinney.   

Abstract

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Year:  2000        PMID： 11112609     DOI： 10.1021/jo0004761

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


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  5 in total

1.  Solution-phase parallel synthesis of a multi-substituted benzo[b]thiophene library.

Authors:  Chul-Hee Cho; Benjamin Neuenswander; Gerald H Lushington; Richard C Larock
Journal:  J Comb Chem       Date:  2009 Sep-Oct

2.  Structure Guided Design, Synthesis, and Biological Evaluation of Novel Benzosuberene Analogues as Inhibitors of Tubulin Polymerization.

Authors:  Haichan Niu; Tracy E Strecker; Jeni L Gerberich; James W Campbell; Debabrata Saha; Deboprosad Mondal; Ernest Hamel; David J Chaplin; Ralph P Mason; Mary Lynn Trawick; Kevin G Pinney
Journal:  J Med Chem       Date:  2019-05-24       Impact factor: 7.446

3.  Mechanistic Considerations in the Synthesis of 2-Aryl-Indole Analogues under Bischler-Mohlau Conditions.

Authors:  Matthew T MacDonough; Zhe Shi; Kevin G Pinney
Journal:  Tetrahedron Lett       Date:  2015-06-03       Impact factor: 2.415

4.  Structural interrogation of benzosuberene-based inhibitors of tubulin polymerization.

Authors:  Christine A Herdman; Laxman Devkota; Chen-Ming Lin; Haichan Niu; Tracy E Strecker; Ramona Lopez; Li Liu; Clinton S George; Rajendra P Tanpure; Ernest Hamel; David J Chaplin; Ralph P Mason; Mary Lynn Trawick; Kevin G Pinney
Journal:  Bioorg Med Chem       Date:  2015-12-15       Impact factor: 3.641

5.  Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3',4',5'-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold.

Authors:  Romeo Romagnoli; Filippo Prencipe; Paola Oliva; Barbara Cacciari; Jan Balzarini; Sandra Liekens; Ernest Hamel; Andrea Brancale; Salvatore Ferla; Stefano Manfredini; Matteo Zurlo; Alessia Finotti; Roberto Gambari
Journal:  Molecules       Date:  2020-04-07       Impact factor: 4.411
  5 in total

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