| Literature DB >> 11112601 |
M P Jennings1, E A Cork, P V Ramachandran.
Abstract
Catalytic amounts of zinc, as low as 10 mol %, in the presence of trifluoroacetic acid (TFA) initiate the radical addition of perfluoroalkyl iodides to terminal alkynes with high regio- and stereoselectivities. Palladium-mediated cross-coupling of these (E)-perfluoroalkyl vinyl iodides allows for a facile synthesis of potentially useful fluoroorganic intermediates.Entities:
Year: 2000 PMID： 11112601 DOI： 10.1021/jo001318c
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354